Multinuclear multibenzimidazole metal complexes frequently exhibit novel structures and properties, and are an example of versatile compounds in bioinorganic chemistry. In this work, first, we synthesized the mononuclear complex [Cu(ntb)(H(2)O)](2+), 1, by using tris[(benzimidazol-2-yl)methyl]amine (ntb). Then, a library of multicationic ntb-Cu(II) complexes, 2-9, was prepared by replacing the ...

To test whether the anorexia and host depletion following doxorubicin chemotherapy can be improved by concomitant insulin therapy, 70 F344 rats were divided equally between tumor-bearing (TB) and non-tumor-bearing (NTB) groups and studied for food intake, host weight, and tumor size changes. Sarcoma fragments were implanted s.c. in TB rats and 18 days later all rats received an i.v. dose of dox...

Nontariff barriers (NTBs) refer to the wide range of policy interventions other than border tariffs that affect trade of goods, services, and factors of production. Most taxonomies of NTBs include market-specific trade and domestic policies affecting trade in that market. Extended taxonomies include macro-economic policies affecting trade. NTBs have gained importance as tariff levels have been ...

• Welfare effects of taxation and other costs under imperfect competition are analyzed. Formulas for the marginal value public funds incidence provided. Our framework can be readily extended to encompass firm heterogeneity. This paper provides a comprehensive study welfare multiple policy interventions external changes with emphasis on specific ad valorem as leading case. Specifically, in relat...

This study examines the impact of the use of new-technology based (NTB) interpersonal communication media on user perception and behavior in social contexts. As a first step, general beliefs based on the media richness theory are examined. In particular, the synchrony and symmetry model is examined in terms of its relevance in explaining the characteristics of NTB media. A new three-dimensional...

Background Economic theory predicts that the excise tax structure influences distribution of cigarette prices. Evidence shows uniform specific structures exhibit least price variability relative to other structures. The prices under different has never been examined for a group African countries. Objectives To examine in nine countries and critically evaluate effectiveness regional directives p...

This paper proposes a novel strategy for identifying the effects of import competition on economic outcomes that avoids standard concerns related to endogeneity trade policy and provides consistent measure exposure over time. Conditioning level tariffs, our approach exploits cross-industry differences in relative importance specific rather than ad valorem tariffs. As they are expressed per unit...

Expert Statement: Souvenaid® – A Dietary Supplement in the Treatment of Early Alzheimer’s Disease. Alzheimer’s disease is a progressive neurological disease characterised by amyloid plaque formation, neurofi brillary tangles, and synapse loss. Memory loss is an early event in the progression of Alzheimer’s disease. Data from preclinical trials showed that it is possible to improve memory functi...

Trogocytosis, the transfer of membrane patches from target to immune effector cells, is a signature of tumor-T cell interaction. In this study, we used the trogocytosis phenomenon to study functional diversity within tumor-specific T cell clones with identical TCR specificity. MART-1(26-35)-specific CD8 T cell clones, which differed in their trogocytosis capacity (low [2D11], intermediate [2G1]...

We read with interest the observational study by Paula Ramirez et al. [1] discovering the appropriate starting time of antibiotic treatment in patients with ventilatorassociated pneumonia (VAP). In that study, 440 patients receiving mechanical ventilation were screened, but only patients with VAP were studied, including 43 with gradual VAP and 28 with non-gradual VAP, and they suggested that ea...