نتایج جستجو برای: adamantane
تعداد نتایج: 671 فیلتر نتایج به سال:
In this communication we present a new synthetic strategy to different generation Hydra-like dendrons based on tetrafunctionalized adamantane as a building block. The novel dendrons, which we termed HYDRAmers, possess at the periphery and at the central core orthogonal protections that can be exploited for conjugation of targeting ligands, drugs and/or imaging probes.
We describe here the sugar functionalized β-cyclodextrin-ferrocene glass slides as fully reversible bacterial biosensors under the influence of external adamantane carboxylic acid. The prototype d-mannose - E. coli ORN 178 and l-fucose - P. aeruginosa interactions serve as a model to illustrate the new approach.
CONTEXT The adamantanes, amantadine and rimantadine, have been used as first-choice antiviral drugs against community outbreaks of influenza A viruses for many years. Rates of viruses resistant to these drugs have been increasing globally. Rapid surveillance for the emergence and spread of resistant viruses has become critical for appropriate treatment of patients. OBJECTIVE To investigate th...
Increased bacterial resistance to antibiotics is a major threat human health, and it particularly important develop novel antibiotic drugs. Here, we designed series of Schiff base thiosemicarbazone derivatives containing an adamantane moiety, carried out the structural characterization compounds in vitro antibacterial activity tests. Compound 7e was as effective commonly used ampicillin against...
In this report, we describe the first isolation and structural verification of the diamondoid cyclohexamantane, C26H30, a material that has probably never previously existed anywhere in crystalline form. Since the diamond surface can terminate in hydrogen,[1] cyclohexamantane may be thought of as a nanometer-sized diamond of approximately 10 21 carats. In fact, the cyclohexamantane structure ha...
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