Genetic research on addiction liability and pharmacogenetic research on treatments for addiction have identified some genetic variants associated with disease risk and treatment. Genetic testing for addiction liability and treatment response has not been used widely in clinical practice because most of the genes identified only modestly predict addiction risk or treatment response. However, man...

Is the Addiction Severity Index–Multimedia Version a viable alternative to the expensive and potentially unreliable Standard Addiction Severity Index? The Addiction Severity Index– Multimedia Version is a CD-ROM based simulation of the interviewer-administered Standard Addiction Severity Index (ASI-MV, 2003). This study has clients in treatment self-administer the Addiction Severity Index – Mul...

ALTHOUGH 13 MILLION TO 16 MILLION PEOPLE IN THE UNITED States each year could benefit from treatment for addiction disorders, less than 25% of them receive it. Negative attitudes of physicians toward diagnosis and treatment of addiction create barriers to their early identification and treatment. In one survey of general practice physicians and nurses, a majority believed that no available medi...

background emotional conditions governing the family and patients’ perceived social support play important roles in the treatment or relapse process of the chronic disease. objectives the current study aimed to investigate the role of family expressed emotion and perceived social support in prediction of addiction relapse. patients and methods the descriptive-correlation method was used in the ...

results results showed that there was a significant difference between the experimental and control groups in terms of depression and temping beliefs (p < 0.0001). in other words, the results showed that cognitive-behavior therapy reduces depression and improves craving beliefs of abusers under methadone maintenance treatment. objectives this study aimed at investigating the effectiveness of co...

There are currently effective, U.S. Food and Drug Administration (FDA)-approved therapies for alcohol, nicotine, and opioid addiction. In some cases these therapeutics were rationally designed and tested using a combination of various animal models of addiction. In many cases, however, effective drug therapies for addiction were derived from the testing of compounds developed for other CNS diso...

New scientific knowledge and effective, evidence-based interventions have provided health leaders and policymakers a remarkable paradigm to guide the development of addiction treatment services around the world. The definition of addiction as a brain disease, validated screening and assessment tools, medication-assisted treatment, and effective behavioral treatments have served as vehicles for ...

Privately funded addiction treatment programs were surveyed to increase understanding of assessment and current treatment options for patients with co-occurring substance use and eating disorders. Data were collected from face-to-face interviews with program administrators of a nationally representative sample of 345 private addiction treatment programs. Although the majority of programs report...

Addiction or substance dependence is a psychiatric disorder that affects many individuals in the general population. Different theories concerning the neurobiological aspects of addiction have been proposed. Special attention has been paid to models concerning dysregulation of the reward circuit and the inhibitory control system within the cortico-basal ganglia-thalamocortical pathways. In the ...