The potent mycotoxin aflatoxin B1 is a secondary metabolite of Aspergillus fungi that grow, on a variety of food and feed commodities at any stage during growth, harvest, storage and transportation. The occurrence of aflatoxin contamination is global, with severe problems especially prevalent in developing countries. In present study, corn samples were contaminated with aflatoxin B1 in the conc...

Rat cecal microflora from high- and low-fiber-fed animals hydrolyzed aflatoxin conjugates to metabolites indistinguishable from aflatoxin B1 and aflatoxin P1, but aflatoxicol was not a transformation product.

Four oilseeds providing cocoa-butter substitutes--shea, pentadecima, illipe, and salseed--when tested as substrates for aflatoxin production by two strains of Aspergillus parasiticus, gave varying levels of aflatoxin. Aflatoxins were found at low levels occurring naturally in moldy shea-nuts, but none of 21 commercial shea-nut samples contained greater than 20 micrograms of aflatoxin B1 per kg.

Aflatoxin B1 (AFB1) and its metabolite aflatoxin M1 (AFM1) are well-known carcinogens for humans and animals health. In this study, an ultra-high performance liquid chromatography linked with fluorescence detection (UPLC-FLD) method was optimized and validated. In addition, we investigated for the first time, the influence of curcumin on residue depletion of AFB1 and AFM1 in liver, kidney, and ...

Thirty different isolates of actinomycetes collected from different localities in Gharbia Governorate, Egypt were tested for melanin pigment production. Only one isolate produced melanin and identified as Streptomyces torulosus. The selected actinomycete isolate was grown under different cultural conditions and it was found that starch-nitrate medium was the optimum for the growth of selected i...

Aflatoxins are a family of toxic, acetate-derived decaketides that arise biosynthetically through polyhydroxyanthraquinone intermediates. Most studies have assumed that aflatoxin B1 is the biosynthetic precursor of the other aflatoxins. We used a strain of Aspergillus flavus which accumulates aflatoxin B2 to investigate the later stages of aflatoxin biosynthesis. This strain produced aflatoxins...

BACKGROUND The leaves of Ocimum basilicum L. (basil) are used in traditional cuisine as spices; its essential oil has found a wide application in perfumery, dental products as well as antifungal agents. AIM To assess the chemical composition as well as the in vitro antifungal activity of O. basilicum L. essential oil against Aspergillus flavus fungal growth and aflatoxin B1 production. MATE...

1.1 Enzymatic sensory detection of sterigmatocystin The development of fast and sensitive sensor for mycotoxins’ detection has drawn a great attention in resent years (Prieto-Simom, B. et al., 2007). However, to construct antiinterference biosensor for the practical samples is still challenge. Sterigmatocystin, a biogenic precursor of aflatoxin B1, has been classified as group 2B by the Interna...

Aflatoxin B1-contaminated feeds and foods induce various health problems in domesticated animals humans, including tumor development hepatotoxicity. B1 also has embryotoxic effects different livestock species humans. However, it is difficult to distinguish between the indirect, maternally-mediated toxic direct embryotoxicity of aflatoxin mammals. In present study, we investigated B1-induced a z...

A 3-year comprehensive analysis of aflatoxin contamination in peanut butter was conducted in Zambia, sub-Saharan Africa. The study analyzed 954 containers of 24 local and imported peanut butter brands collected from shops in Chipata, Mambwe, Petauke, Katete, and Nyimba districts and also in Lusaka from 2012 to 2014. For analysis, a sample included six containers of a single brand, from the same...