Reexamining experimental data of single-molecule fluorescence correlation spectroscopy for cholesterol oxidase, we find that the existing Michaelis-Menten models with dynamical disorder cannot explain strong correlations between subsequent turnover cycles revealed in the diagonal feature in the joint statistical distribution of adjacent "on" times of this enzyme. We suggest that functional conf...

A new technique was recently developed to study seasonal cycles of climatic trends of expected values, variance, skewness, and other statistical moments of climatic variables. Here we apply that technique to analyze the diurnal and seasonal cycles of trends of surface air temperature and its variability using hourly observations from nine geographically distributed meteorological stations in th...

Relaxation phenomena in disordered systems are often described by stretched exponentials; such behavior has traditionally been explained by invoking statistical distributions. In hydrogenated amorphous silicon, the relaxation has been associated with dispersive diffusion of hydrogen, related to a distribution of energies for trap states and barrier heights. Here we show that invoking such energ...

Let a1, . . . , an, b1, . . . , bn be random variables in some (non-commutative) probability space, such that {a1, . . . , an} is free from {b1, . . . , bn}. We show how the joint distribution of the n-tuple (a1b1, . . . , anbn) can be described in terms of the joint distributions of (a1, . . . , an) and (b1, . . . , bn), by using the combinatorics of the n-dimensional R-transform. We point out...

The count of the nucleotides in a cloned, short genomic sequence has become an important criterion to annotate such a sequence as a miRNA molecule. While the majority of human mature miRNA sequences consist of 22 nucleotides, there exists discrepancy in the characteristic lengths of the miRNA sequences. There is also a lack of systematic studies on such length distribution and on the biological...

In this paper, we present an approach to execute more realistic traffic sources in network simulators (like Network Simulator 2) for fixed and mobile networks. Traffic source models can be defined from network measures to give an accurate statistical distribution of inter-arrival time and packet size at packet level. These traffic sources models can be integrated into a network simulator to per...

OBJECTIVES The aim of the study was to describe the ageing HIV-infected population (> 50 years old) and their current antiretroviral therapy (ART), comorbidities and coprescriptions in France in 2013 and to compare them to the younger population. METHODS A retrospective analysis of a prospectively collected database was performed. The characteristics of patients receiving ART as well as their...

The Australian health care system is currently in a state of reform and there is increasing pressure to provide care in community settings. Rising costs, demands and population ageing underscore the importance of adopting models of health care delivery to address changing epidemiological patterns. Population ageing and the increase of chronic conditions challenge models based on acute care. Cha...

OBJECTIVES Uncertainty about the timing of a known external event is an everyday phenomenon but has been rarely investigated with electrophysiological methods. We studied how the amplitude of the contingent negative variation (CNV) is affected by temporal variation of S2 presentation. Competing hypotheses about the development of CNV during the foreperiod until S2 presentation were that CNV eit...

Determining the age of sharks using vertebral banding is a vital component of management, but the causes of banding are not fully understood. Traditional shark ageing is based on fish otolith ageing methods where growth bands are assumed to result from varied seasonal calcification rates. Here we investigate these assumptions by mapping elemental distribution within the growth bands of vertebra...