felodipine is a second generation calcium channel blocker widely used as antihypertensive and antianginal drug which belongs to bcs class ii category. hence, its low water solubility limits the pharmacological effect. the aim of this study was to improve the dissolution rate of felodipine using spherical agglomeration technique with acetone, water and dichloromethane as good solvent, poor solve...

In this article the concept of territorial agglomeration is discussed and reflected from the point of view of innovation activities. From this same angle, some suggestions are also made as to how to bring some clarity to the complex issue of the relationship between companies and their local operational environment. One of the conclusions is that a territorial agglomeration can be a basis for s...

Understanding and controlling powder de-agglomeration is of great importance in the development of dry powder inhaler (DPI) products. Dry dispersion laser diffraction measures particle size readily under controlled dispersing conditions, but has not been exploited fully to characterise inherent powder dispersibility. The aim of the study was to utilise particle size-dispersing pressure titratio...

With industrial integration accelerating in domestic and foreign enterprise, industrial integration is becoming the only way for regional development to break through its bottleneck. Compared with advanced foreign enterprises, there exists a significant gap in regional industrial integration, especially in the urban agglomeration of the energy chemical industries of Urumqi-Changji-Shihezi in Xi...

Bearing the responsibility of the rising strategy of central region of China, Changsha-Zhuzhou-Xiangtan Urban Agglomeration is an important growth pole of the development of the Yangtze river economic belt. Reasonable position of urban function in Changsha-Zhuzhou-Xiangtan Urban Agglomeration, is an inevitable requirement for the cooperative development of regional economy in Changsha, Zhuzhou ...

The presence of Chinese multinational enterprises (MNEs) in Europe is on the rise, yet they concentrate specific regions. Traditional spatial explanations this clustering refer to co-location foreign and local firms same or related sectors (‘industry agglomeration’). Nonetheless, investors may also favour locations with a ethnic communities (‘country-of-origin We investigate combined role both ...

The increase in wage inequality since 1980 in the United States has been more pronounced in larger cities, even after accounting for di¤erences in the composition of the workforce across locations. Using Census of Population and Census of Manufacturers data aggregated to the local labor market level, this paper examines the importance of changes in the factor bias of agglomeration economies, ca...

This paper demonstrates the optical trapping of micron-sized gold nanoparticle aggregates GNAs with a TEM00 mode laser at 532 nm and reports the observation of an unusual light-induced agglomeration phenomenon that occurs besides the trapping of the GNAs. The observed agglomerate has a 60–100 m donut-shaped metal microstructure with the rate of formation dependent on the laser power used. Citra...

Entropy Agglomeration (EA) is a hierarchical clustering algorithm introduced in 2013. Here, we generalize it to define Generalized Entropy Agglomeration (GEA) that can work with multiset blocks and blocks with rational occurrence numbers. We also introduce a numerical categorization procedure to apply GEA to numerical datasets. The software REBUS 2.0 is published with these capabilities: http:/...

A rapid and facile signal enhancement method for detecting alpha-fetoprotein (AFP) was developed using the magnetic agglomeration of ferromagnetic nanoparticles and microcantilever sensors. The resonance frequency and deflection of the cantilevers were found to be more than 10-fold greater than that before physical agglomeration of the free nanoparticles around the magnetized nanoparticles.