BACKGROUND The usefulness of the 2013 ACC/AHA guidelines for the management of blood cholesterol in the Asian population remains controversial. In this study, we investigated whether eligibility for statin therapy determined by the 2013 ACC/AHA guidelines is better aligned with the presence of subclinical coronary atherosclerosis detected by CCTA (coronary computed tomography angiography) compa...

TBD, 2016 e1 CLICAL SATEM ENTS ND GUELINES The intent of this American Heart Association (AHA) scientific statement is to summarize our current understanding of dilated cardiomyopathies. There is special emphasis on recent developments in diagnostic approaches and therapies for specific cardiomyopathies. Recommendations in this document are based on published studies, published practice guideli...

BACKGROUND/AIMS The immunoregulatory molecules programmed death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) are associated with the dysfunction of antiviral effector T-cells, which leads to T-cell exhaustion and persistent viral infection in patients with chronic hepatitis C and chronic hepatitis B. Little is known about the role of PD-1 and CTLA-4 in patients with symptom...

Abstract: Sudden death in young athletes remains a distressing societal problem. The American Heart Association (AHA) 12-point questionnaire (AHAQuest) has been recommended as a cost-effective initial step in pre-participation screening for athletes. We prospectively tested the efficacy of the AHA approach in a comprehensive, Circulation 23 November 2010, Volume 122, Issue Suppl 21 & Table of

This work was supported by a National Multiple Sclerosis Society postdoctoral fellowship to N.L.M. and NIH/ NINDS grants R01NS051470 and R01NS052189 to K.A. V.A.R is an American Heart Association (AHA) postdoctoral fellow and D.D. holds Scientist Development Grant 13SDG17210051 from AHA. The J. David Gladstone Institutes received support from a National Center for Research Resources (grant RR18...

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In this semiannual update, we will review current American Heart Association/American Stroke Association (AHA/ ASA) initiatives for stroke, changes to the process for developing guidelines and scientific statements, updates on research funding, and the upcoming International Stroke Conference. Before the updates, we will first review the AHA/ASA mission and goals and the role of the Stroke Coun...

BACKGROUND/AIMS The nonspecific clinical presentation of acute hepatitis A (AHA) mandates the detection of anti-hepatitis A virus IgM antibodies (IgM anti-HAV) in the serum for obtaining a definitive diagnosis. However, IgM anti-HAV might not be present during the early phase of the disease. The aim of this study was to determine the optimal time for repeating the IgM anti-HAV test (HAV test) i...

PURPOSE The aim of this statement is to summarize data on stroke risk factors that are unique to and more common in women than men and to expand on the data provided in prior stroke guidelines and cardiovascular prevention guidelines for women. This guideline focuses on the risk factors unique to women, such as reproductive factors, and those that are more common in women, including migraine wi...

BACKGROUND The 2007 update to the American Heart Association (AHA) guidelines for cardiovascular disease prevention in women recommend a simplified approach to risk stratification. We assigned Women's Health Initiative participants to risk categories as described in the guideline and evaluated clinical event rates within and between strata. METHODS AND RESULTS The Women's Health Initiative en...