Analytic Hierarchy Process (AHP) is major method for decision making now and decision maker’s answers are strongly related to his or her cognitive abilities. Inner dependence AHP is used for cases in which criteria or alternatives are not independent enough. In the process, calculations and compositions of weights are very important steps. Using the original AHP or inner dependence AHP may caus...

Modulation of afterhyperpolarization (AHP) represents an important mechanism by which excitability of a neuron can be regulated. In the leech brain, sensitization enhances excitability of the S-cell, an interneuron thought to play an important role in this form of nonassociative learning. This increase in excitability is serotonin (5-HT) dependent, but it is not known whether changes in AHP con...

The fundamental problem underlying all multi-criteria decision analysis (MCDA) problems is that of dominance between any two alternatives: ‘Given two alternatives A and B, each described by a set criteria, is A preferred to B with respect to a set of decision maker (DM) preferences over the criteria?’. Depending on the application in which MCDA is performed, the alternatives may represent strat...

Whole cell patch and cell-attached recordings were obtained from neurons in intact ganglia of the myenteric plexus of the guinea pig duodenum. Two classes of neuron were identified electrophysiologically: phasically firing AH neurons that had a pronounced slow afterhyperpolarization (AHP) and tonically firing S neurons that lacked a slow AHP. We investigated the properties of the slow AHP and t...

BACKGROUND Patient involvement is widely acknowledged to be a valuable component in health technology assessment (HTA) and healthcare decision making. However, quantitative approaches to ascertain patients' preferences for treatment endpoints are not yet established. The objective of this study is to introduce the analytic hierarchy process (AHP) as a preference elicitation method in HTA. Based...

The sorting problem in the Multi-criteria Decision Analysis (MCDA) has been used to address issues whose solutions involve allocation of alternatives classes. Traditional multi-criteria methods are commonly for this task, such as ELECTRE TRI, AHP-Sort, UTADIS, PROMETHEE, GAYA, etc. While using these approaches perform procedure, decision-makers define profiles (thresholds) classes compare withi...

Bilgi güvenliği kişilerin, şirketlerin, kurumların ve ülkelerin maddi manevi zarar görmemesi için en etkin şekilde yönetilmesi gereken bir süreçtir. Endüstri 4.0 ile farklı boyut kazanan bilginin dijital ortama aktarılması ortamda işlenebiliyor olması siber güvenlik konusunu kritik noktaya taşımaktadır. Çünkü sahibi olan kişiden ülke ölçeğine kadar güvenliğin sağlanmaması kayıpların yanında ger...

The slow Ca2+-activated K+ current (sI(AHP)) plays a critical role in regulating neuronal excitability, but its modulation during abnormal bursting activity, as in epilepsy, is unknown. Because synaptic transmission is enhanced during epilepsy, we investigated the synaptically mediated regulation of the sI(AHP) and its control of neuronal excitability during epileptiform activity induced by 4-a...