Aging is a phenomenon that presents various alterations in neurochemical, behavioral and physiological processes. This study aimed to evaluate the effect of aging on the histology of the duodenum of male albino rats. Fifteen male albino rats were divided into three groups of 5 rats each: Group A: Included rats at the age of 2 months. Group B: Rats were continued to live to the age of 6 months a...

Immunohistochemical localization of islets of Langerhans of streptozotocin (65 mg/kg, ip) induced diabetic + glurenorm (10 mg/kg, po) treated female albino rats revealed increase in number of beta cells and insulin immunoreactivity of beta cells. The results suggest that glurenorm can cause the stimulation of beta cells of endocrine pancreas in diabetic rats.

by late 18th or early 19th century, albino rats became the most commonly used experimental animals in numerous biomedical researches, as they have been recognized as the preeminent model mammalian system. but, the precise correlation between age of laboratory rats and human is still a subject of debate. a number of studies have tried to detect these correlations in various ways. but, have not s...

objective: n-nitroso-n-methylurea (nmu) induces breast cancer in rodents, particularly in rats. this model of breast cancer is very similar to human breast cancer. as a continuation of our recent work, we investigated the expressions of cyclin d1 and p21 in nmu-induced breast cancer of wistar albino rats. materials and methods: in this experimental study, mammary carcinoma was induced in female...