In this work, a reversed-phase liquid chromatographic (RP-LC) method has been developed for the determination of alogliptin (ALG) based on isocratic elution using a mobile phase consisting of potassium dihydrogen phosphate buffer pH (4.6)-acetonitrile (20:80, v/v) at a flow rate of 1 mL min(-1) with UV detection at 215 nm. Chromatographic separation was achieved on a Symmetry(®) cyanide column ...

We apply classical proof complexity ideas to transfer lengths-of-proofs lower bounds for a propositional proof system P into examples of hard unsatisfiable formulas for a class Alg(P ) of SAT algorithms determined by P . The class Alg(P ) contains those algorithms M for which P proves in polynomial size tautologies expressing the soundness of M . For example, the class Alg(Fd) determined by a d...

Water-soluble fluorescent colloidal quantum dots (QDs) have been widely used in some biological and biomedical fields, so the interaction of QDs with biomolecules recently attracts increasing attention. In this paper, CdTe quantum dots modified by a natural biopolymer based on polyacrylamide (PAAm) grafted onto sodium alginate (Alg-g-PAAm) were synthesized in an aqueous solution. Then, the bind...

In an earlier paper, the authors showed that standard semigroups M1, M2 andM3 play an important role in the classification of weaker versions of alg-universality of semigroup varieties. This paper shows that quasivarieties generated by M2 and M3 are neither relatively alg-universal nor Q-universal, while there do exist finite semigroups S2 and S3 generating the same semigroup variety as M2 and ...

BACKGROUND The role of thoracic paravertebral blockade (TPVB) in decreasing opioid requirements in breast cancer surgery is well documented, and there is mounting evidence that this may improve survival and reduce the rate of malignancy recurrence following cancer-related mastectomy. We compared the two techniques currently in use at our institution, the anatomic landmark-guided (ALG) multileve...

The significance and extent of Ca(2+) regulation of the biosynthetic secretory pathway have been difficult to establish, and our knowledge of regulatory relationships integrating Ca(2+) with vesicle coats and function is rudimentary. Here, we investigated potential roles and mechanisms of luminal Ca(2+) in the early secretory pathway. Specific depletion of luminal Ca(2+) in living normal rat ki...

Trans-cinnamic acid and p-coumaric are valuable intermediates in the synthesis of flavonoids widely employed food, flavor pharmaceutical industries. These products can be produced by deamination L-phenylalanine L-tyrosine catalyzed phenylalanine ammonia lyase or tyrosine lyase. Phenylalanine ammonia-lyase (PAL, EC 4.3.1.5) from Rhodotorula glutinis do not exhibit strong substrate specificity co...

AT A SIMILAR MEETING in] une of 1966, also held at Brook Lodge, we presented data from more than 200 canine experiments which were designed (8, 26, 27) to determine: 1) what magnitude of immunosuppression could be expected in dogs from treatment with small volumes of antilymphocyte sera (ALS) possessing high antiwhite blood cell titers, 2) what were the toxic effects of this kind of therapy, an...

The goal of this paper is to explain the analogy between certain results in algebraic geometry, namely the Riemann-Roch theorems due to Baum,Fulton, and MacPherson ([BFM2],and [FMac]); and recent results in geometric topology due to Dwyer, Weiss and myself [DWW]. One reason for doing this is that the bivariant viewpoint introduced by Fulton-MacPherson in their memoir [FMac], becomes particularl...

This paper is devoted to an online variant of the minimum spanning tree problem in randomly weighted graphs. We assume that the input graph is complete and the edge weights are uniform distributed over [0, 1]. An algorithm receives the edges one by one and has to decide immediately whether to include the current edge into the spanning tree or to reject it. The corresponding edge sequence is det...