Heterotrophic bacteria associated with two specimens of the marine sponge Erylus discophorus were screened for their capacity to produce bioactive compounds against a panel of human pathogens (Staphylococcus aureus wild type and methicillin-resistant S. aureus (MRSA), Bacillus subtilis, Pseudomonas aeruginosa, Acinetobacter baumanii, Candida albicans and Aspergillus fumigatus), fish pathogen (A...

Resolving the enzymatic pathways leading to sialic acids (Sias) in bacteria are vitally important for understanding their roles in pathogenesis and for subsequent development of tools to combat infections. A detailed characterization of the involved enzymes is also essential due to the highly applicable properties of Sias, i.e., as used in a wide range of medical applications and human nutritio...

Hemp, flax and canola seed cakes are byproducts of the plant oil extraction industry that have not received much attention in terms of their potential use for human food instead of animal feed. Thus, the bioactivity profiling of these oilseed cakes is of interest. For their effect-directed analysis, planar chromatography was combined with several (bio)assays, namely 2,2-diphenyl-1-picrylhydrazy...

BACKGROUND The ferric uptake regulator (Fur) is a transcription factor and the main regulator of iron acquisition in prokaryotes. When bound to ferric iron, Fur recognizes its DNA binding site and generally executes its function by repressing transcription of its target genes. Due to its importance in virulence, the Fur regulon is well studied for several model bacteria. In our previous work, w...

Abstract UV filters in environmental compartments are a source of concern related to their ecotoxicological effects. However, little is known about filters’ toxicity, particularly those released into the environment as mixtures. Acute toxicity nine organic benzophenone-1, benzophenone-2, benzophenone-3, 4-methoxy benzylidene camphor, octocrylene, ethylhexyl methoxycinnamate, 2-ethylhexyl salicy...

Polyurethanes (PUs) are an exceedingly heterogeneous group of plastic polymers, widely used in a variety industries from construction to medical implants. In the past decades, we have witnessed accumulation PU waste and its detrimental environmental impacts. PUs been identified as one most toxic polymers leaching hazardous compounds derived both polymer itself additives production. Further impa...

Antihypertensive drugs are among the most prescribed drugs. Olmesartan acid, of sartan class, belongs to a relatively new generation antihypertensive called angiotensin II receptor blockers. There very few studies on presence and fate sartans in environment, despite them being marketed huge quantities, metabolized low percentages, detected wastewater water bodies. This paper presents study less...