background: regulatory cd4+t (treg) cells are effective in maintaining immune tolerance. objective: to investigate single nucleotide polymorphisms (snps) of transforming growth factor β-1 (tgf-β1) and forkhead box protein 3 (foxp3) genes in iranian patients with allergic rhinitis (ar). methods: variations at codons 10 and 25 of tgf-β1 and foxp3 at positions -3279 a>c and -924 a>g were evaluated...

background: contact dermatitis (cd) is a significant problem among nurses. although there are reports about the prevalence of cd from different parts of the world, data about its frequency in turkey and about allergic contact sensitization among nurses is insufficient. objective: to define the frequency and patterns of allergic contact sensitization and related symptoms in practicing and studen...

introduction allergic rhinitis, like other allergic diseases, is one of the most common disorders during childhood; this study was conducted to assess and compare the prevalence and severity of allergic rhinitis in children and adolescents living in kurdistan province. the study was aimed to provide a ground for the identification of likely causes and risk factors of this disorder. materials an...

inhalation of fungal spores is shown to participate in the development of allergic rhinitis symptoms. in this study, relation between presence of alternaria in the human nasal cavity and allergic rhinitis is assessed. in a case-control study, 58 allergic rhinitis patients were compared with a well-matched control group of fifty healthy volunteers for sensitization to alternaria (by skin prick t...

allergic rhinitis is a chronic respiratory disease. sympathetic hypofunction is identified in all of the allergic rhinitis patients. moreover, allergic rhinitis is associated with decreased peak nasal inspiratory flow (pnif) and impaired lung functions. the aim of this study was to investigate effects of six-week of aquatic exercise on the autonomic nervous system function, pnif and lung functi...

component-resolved  diagnosis (crd) using microarray technology has recently been introduced  with the  aim to  improve diagnosis of allergy. the  aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (spt). 45  patients  with  allergic rhinitis  were studied  (16 children  and  29  adults). spt  to dermatophagoides ...

Allergic asthma, an inflammatory disease characterized by the infiltration and activation of various leukocytes, the production of Th2 cytokines and leukotrienes, and atopy, also affects the function of other cell types, causing goblet cell hyperplasia/hypertrophy, increased mucus production/secretion, and airway hyperreactivity. Eosinophilic inflammation is a characteristic feature of human as...

UNLABELLED HIF-1α is a transcription factor that is activated during hypoxia and inflammation and is a key regulator of angiogenesis in vivo. During the development of asthma, peribronchial angiogenesis is induced in response to aeroallergens and is thought to be an important feature of sustained chronic allergic inflammation. Recently, elevated HIF-1α levels have been demonstrated in both the ...