Background:Â Malaria is an endemic disease that can lead to death. control a threatening cause of resistance antimalarial drugs so renewable therapies are needed overcome this disease. The chemical compounds garlic have potential as agents, but the mechanism still unknown. Aim:Â This research will predict compounds' molecular in (Allium sativum) using in-silico method. Methods:Â In-silico metho...

BACKGROUND In the present study, we investigated the effects of oil products from two Allium species: Allium sativum (garlic) and Allium hookeri (Chinese chives) on cell proliferation and neuroblast differentiation in the mouse dentate gyrus. METHODS Using corn oil as a vehicle, the essential oil from garlic (10 ml/kg), or Chinese chives (10 ml/kg) was administered orally to 9-week-old mice o...

background & aim: allium sativum commonly known as garlic is an herb used over years to prevent from various ailments such as cardiovascular diseases, cognitive disorders and also enhances the immune system. the aim of the present study is to study the in vitro antiarthritic and antihemolytic potential of garlic in aqueous and methanolic extracts. fourier transform infrared spectroscopy was per...

Effects of garlic (Allium sativum L.) extract on the temporal patterns of circulatory lipid peroxidation products and antioxidants during N-nitrosodiethylamine (NDEA)induced hepatic tumorigenesis were investigated in Wistar rats. Experimental animals were divided into control, NDEA-treated, NDEAþ garlic-treated, and garlictreated. The characteristics of circadian rhythms (acrophase, amplitude, ...

The effects of zinc oxide nanoparticles (ZnO NPs) on the root growth, root apical meristem mitosis and mitotic aberrations of garlic (Allium sativum L.) were investigated. ZnO NPs caused a concentration-dependent inhibition of root length. When treated with 50 mg/L ZnO NPs for 24 h, the root growth of garlic was completely blocked. The 50% inhibitory concentration (IC(50)) was estimated to be 1...

By using agar well diffusion assay, antifungal activity of aqueous extract prepared from Egyptian garlic (Allium sativum L.) was evaluated in vitro against two strains of Aspergillus flavus (OC1 and OC10) causing human ocular infection. The recorded minimum inhibitory concentration (MIC) for growth inhibition of both strains was 3.60 mg/ml. Aqueous garlic extract (AGE) was used in successive in...

This study evaluated the insecticidal activity of garlic, Allium sativum Linnaeus (Amaryllidaceae) essential oil and their principal constituents on Tenebrio molitor. Garlic essential oil, diallyl disulfide, and diallyl sulfide oil were used to compare the lethal and repellent effects on larvae, pupae and adults of T. molitor. Six concentrations of garlic essential oil and their principal const...

the aim of this study was to optimize the encapsulation conditions of garlic oil (go) with β-cyclodextrin (go/β-cd) inclusion complex by the co-precipitation method. response surface optimization of encapsulation of go with β–cd was performed with a three-variable, three-level and the optimum conditions were as follows: temperature: 35oc, core/wall: 8/100, and wall/solvent: 5.5/100. the complex...

Modern garlic (Allium sativum L.) cultivars are sterile and propagated only vegetatively. The recent discovery of fertile genotypes in Central Asia and the restoration of flowering and fertility by environmental manipulations open the way for in-depth florogenetic, genetic, and molecular research in garlic. In the present work, two bolting garlic accessions were employed: #3026, developing norm...

The purpose of this study was to analyze the indolic, phenolic, and fatty acid content and antioxidant activity of garlic sprouts growing in the dark and in the daylight. The pro- or anti-inflammatory properties of the garlic sprout extract were investigated by evaluating the cyclooxygenase-2 (COX-2), prostaglandin E synthase (cPGES), glutathione S transferase (GSTM1), nuclear factor NF-κB, per...