We study topology optimization in quasi-static plasticity with linear kinematic and isotropic hardening using a level-set method. consider the primal variational formulation for problem. This is subjected to penalization regularization, resulting an approximate problem that shape-differentiable. The shape derivative computed adjoint Thanks proposed time discretization of proved be well-posed. F...

Background: TNF-α is a multifunctional proinflammatory cytokine and TGF-β1 is a secretory protein controlling epithelial proliferation and differentiation. Keratocyst presents an aggressive behavior and a growth mechanism different from that of radicular cyst. Aim: In this line, the present study aimed at evaluating TNF-α and TGF-β1 level and its association with histopath...