OBJECTIVE Controversy exists in using alanine aminotransferase (ALT) activity for predicting long-term survival. Therefore, this research study investigated the association between ALT activity and mortality through a systematic review and meta-analysis of previous prospective studies. METHODS Electronic literature databases, including PubMed, Embase, and the Institute for Scientific Informat...

Nonalcoholic fatty liver disease (NAFLD) is emerging as a component of the metabolic syndrome, although it is not known whether markers of NAFLD, including elevated concentrations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALK), predict the development of metabolic syndrome. Our objective was to investigate the associations of elevated AST, AL...

ALT-801, a fusion of interleukin-2 and a single-chain T cell receptor domain specific to a p53 peptide/HLAA*0201 complex, has shown immune cell-mediated activity in human xenograft tumor SCID mouse models and in patients with metastatic malignancies. To further investigate the antitumor efficacy of this fusion protein in immunocompetent mice, we conducted mechanism-of-action studies in an ortho...

We examined the association of serum alanine aminotransferase (ALT) with features of the metabolic syndrome and whether it predicted incident diabetes independently of routinely measured factors in 5,974 men in the West of Scotland Coronary Prevention Study. A total of 139 men developed new diabetes over 4.9 years of follow-up. ALT, but not aspartate aminotransferase, levels increased progressi...

AIMS To compare the effectiveness of selective laser trabeculoplasty (SLT, a 532 nm Nd:YAG laser) with argon laser trabeculoplasty (ALT) in lowering the intraocular pressure (IOP) in patients with medically uncontrolled open angle glaucoma. METHODS A prospective randomised clinical trial was designed. Patients were randomised to treatment with either SLT or ALT and were evaluated at 1 hour, 1...

BACKGROUND Few studies have examined the effect of insulin resistance on the association between alanine aminotransferase (ALT) and metabolic syndrome. The association between ALT levels and metabolic syndrome were determined, independently of insulin resistance in Korean populations. METHODS AND RESULTS The association between ALT and metabolic syndrome were examined in 28,456 subjects who v...

Free boundaries arise as the interface betweenmaterials inwhich thematerials retain some energy. In contrast, the interface represented by a minimal surface lives in an ambient space that is empty. Despite this difference between these two types of interfaces, there are deep connections between them. In a ground-breaking paper in 1980, Alt and Caffarelli showed that strategies and tools from th...

Özet. Java Card platformu ve beraberinde gelen uygulama programlama arayüzü akıllı kart uygulamalarının geniş kullanıma sahip Java programlama dili ile nesne yönelimli olarak geliştirilmesine imkan vermektedir. Ancak işlemci ve bellek yönünden oldukça kısıtlı olan bu kartlar için sadece Java dilinin bir alt kümesi kullanılabilmektedir ve geliştiriciler bilgisayar ve akıllı kart arasındaki paket...