Hypoxia often causes body water deficits (hypohydration, HYPO); however, the effects of HYPO on aerobic exercise performance and prevalence of acute mountain sickness (AMS) at high altitude (ALT) have not been reported. We hypothesized that 1) HYPO and ALT would each degrade aerobic performance relative to sea level (SL)-euhydrated (EUH) conditions, and combining HYPO and ALT would further degr...

BACKGROUND Severe liver fibrosis is common in patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) who have a high alanine aminotransferase (ALT) level. However, little is known about the frequency, liver biopsy findings, and significance of a persistently normal ALT level in coinfected patients. METHODS We analyzed clinical data and histological findings fo...

BACKGROUND Both the serum uric acid (SUA) level and elevated alanine aminotransferase (ALT) are related to metabolic syndrome. However, the association between SUA and elevated ALT has not been elucidated in the general population. The objective of this study was to investigate the association between SUA and elevated ALT in the general population of China; METHODS A total of 11,572 adults (≥...

Cancer cells rely on telomerase or the alternative lengthening of telomeres (ALT) pathway to overcome replicative mortality. ALT is mediated by recombination and is prevalent in a subset of human cancers, yet whether it can be exploited therapeutically remains unknown. Loss of the chromatin-remodeling protein ATRX associates with ALT in cancers. Here, we show that ATRX loss compromises cell-cyc...

Strong alt-induced codes, a particular case of alt-induced codes, has been introduced and considered by D. L. Van and the author in earlier papers. In this note, an algorithm to check whether a regular code is strong alt-induced or not is proposed, and the embedding problem for the classes of prefix (suffix, bifix) strong alt-induced codes in both the finite and regular case is also exhibited.

BACKGROUND/AIMS The treatment for chronic hepatitis C (CHC) is removal of the virus in order to prevent progression to liver cirrhosis and hepatocellular carcinoma (HCC). Few data have been presented regarding the clinical significance of changes in the alanine aminotransferase (ALT) level in this context. We analyzed the patterns of changes in ALT level and investigated the relationship betwee...

The initial stages of spinodal decomposition were studied by subjecting a critical blend of model polyolefins to a pressure quench and monitoring the evolution by time-resolved small angle neutron scattering. Contrary to the predictions of the widely accepted Cahn-Hilliard-Cook theory, we demonstrate that coarsening of the phase-separated structure begins immediately after the quench and occurs...

This paper presents a theoretical model for studying the dynamics of ordering in alloys which exhibit modulated phases. The model is different from the standard time-dependent Ginzburg-Landau description of the evolution of a non-conserved order parameter and resembles the Swift-Hohenberg model. The early-stage growth kinetics is analyzed and compared to the Cahn-Hilliard theory of continuous o...

We establish existence and non-existence results for entire solutions to the fractional Allen-Cahn equation in R, which vanish on helicoids and are invariant under screw-motion. In addition, we prove that helicoids are surfaces with vanishing nonlocal mean curvature.

We study the effect of a higher-order nonlinearity in the standard Kuramoto-Sivashinsky equation: partial differentialxG(Hx). We find that the stability of steady states depends on dv/dq , the derivative of the interface velocity on the wave vector q of the steady state. If the standard nonlinearity vanishes, coarsening is possible, in principle, only if G is an odd function of Hx. In this case...