Ameloblastic carcinoma is a rare malignant lesion with characteristic histologic features and behaviour that dictates a more aggressive surgical approach than that of a simple ameloblastoma. However, reliable evidence of its biologic activity is currently unavailable due to the scarcity of well-documented cases. It occurs primarily in the mandible in a wide range of age groups; no sex or race p...

Parathyroid hormone (PTH)-related protein (PTH-rP) is an important autocrine/paracrine attenuator of programmed cell differentiation whose expression is restricted to the epithelial layer in tooth development. The PTH/PTHrP receptor (PPR) mRNA in contrast is detected in the dental papilla, suggesting that PTHrP and the PPR may modulate epithelial-mesenchymal interactions. To explore the possibl...

Ameloblastic carcinoma is an extremely rare, aggressive malignant epithelial odontogenic tumor with characteristic histologic features and behaviour that dictates a more aggressive surgical approach than that of ameloblastoma. However, reliable evidence of its biologic activity is currently unavailable and our understanding of the histologic features of ameloblastic carcinoma is somewhat vague ...

Ameloblastic fibroma is a rare mixed odontogenic tumor mostly occurring in the posterior region of the mandible. The peripheral variant is very rare and to the best of our knowledge, only three cases have been reported in the English literature. In this report, we describe a case of peripheral ameloblastic fibroma in a 54-year-old woman with two years of follow-up.

Ameloblastic fibroma is a rare mixed odontogenic tumour. Its usual site of occurrence is the posterior mandible, with very few cases being reported from the maxilla. The true nature of the lesion hamartomatous or neoplastic – is still a point of debate. Here, we report a case of ameloblastic fibroma in the anterior maxilla.

OBJECTIVES Recently, three-dimensional printing models based on preoperative computed tomography and magnetic resonance imaging images have been widely used in medical fields. This study presents an effective use of the three-dimensional printing model in exploring complex spatial relationship between the tumour and surrounding tissue and in simulation surgery based planning of the operative pr...

malignant transformation of ameloblastomas arising from an odontogenic cyst or de novo is wellrecognized. malignancies in ameloblastomas may involve metastasis or a local dysplastic change in the tissue. the latter are classified as ameloblastic carcinomas. a 75-year-old male presented with a mandibular cystic swelling, with no evidence of metastasis. dysplastic ameloblastic cells with spindlec...

BACKGROUND In general, Notch is a representative signal which controls morphosis and differentiation of cells, but its role in human odontogenic neoplasms, especially in ameloblastoma and its malignant counterpart, ameloblastic carcinoma, is not known. METHODS We examined Notch1 peptide and its gene (mRNA) in an ameloblastoma (case 1: 27-year-old female, right mandibular tumor) and an amelobl...