نتایج جستجو برای: aminoguanidine
تعداد نتایج: 861 فیلتر نتایج به سال:
The aim of the work was to determine antidiabetic effect a sitagliptin and aminoguanidine combination in rats with experimental diabetes mellitus. Materials methods. study carried out on male Wistar C57BL/KsJ-db/db mice. According models used, it divided into 4 series, which alloxan, steroid-induced (dexamethasone) streptozotocin-nicotinamide-induced mellitus (DM) were formed, respectively, rat...
PURPOSE To investigate the possible protective effects of aminoguanidine (AG ) on lung damage in whole body irradiated rats. METHODS To evaluate the biological damage of radiation on rat lung tissue, lipid peroxidation products were measured using biochemical parameters. Thirty Wistar albino rats were divided into three subgroups: control (C) , irradiation alone (RT), and RT + AG combined. Af...
Diabetic nephropathy is currently the most common cause of end-stage renal disease (ESRD) in the western world. A mouse model for diabetic nephropathy that encompasses the salient features of this disease in the kidney is not available. Here, we report that CD1 mice, in contrast to inbred C57BL/6 and 129Sv strains, develop ESRD associated with prominent tubulointerstitial nephritis and fibrosis...
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