Rat liver tyrosine aminotransferase (L-tyrosine:2oxoglutarate aminotransferase; EC 2.6.1.5.) has been studied thoroughly with respect to its inducibility by various hormones. Recently, it has been shown that this enzyme can be stimulated by cyclic AMP 1 and by theophylline 2, which is capable of elevating intracellular levels of cyclic purine nucleotides. Moreover, this enzyme was shown to be i...

The blue-green alga Anacystis nidulans (strain L 1402-1) was grown at +37 degrees C in air (0.03 vol% CO2 and in air enriched with 3.0 vol% CO2. The effects of several inhibitors on the activity of aminotransferases, 14CO2 fixation and radioactive photosynthetic products of Anacystis were studied. No serine-pyruvate aminotransferase activity could be found in 10-2 M isonicotinyl hydrazide (INH)...

(EC 2.6.1.5,1 L-tyrosrne : 2-oxoglutarate aminotransferase), alanine aminotransferase (EC 2.6.1.2, L-alaflme :2-oxoglutarate aminotransferase), and aspartate aminotrans ferase (EC 2.6.1.1, L-aspartate : 2-oxoglutarate aminotransferase) in tumor-bearing rats. From the results and studies on various analogous conditions, the metabolism of tumor-bearing animals is discussed. It was found that the ...

In the mosquito, transamination of 3-HK (3-hydroxykynurenine) to XA (xanthurenic acid) is catalysed by an AGT (alanine glyoxylate aminotransferase) and is the major branch pathway of tryptophan metabolism. Interestingly, malaria parasites hijack this pathway to use XA as a chemical signal for development in the mosquito. Here, we report that the mosquito has two AGT isoenzymes. One is the previ...

Tryptophan is recognized to be the precursor of the plant hormone indolylacetic acid. The role of tryptophan in the biosynthesis of the auxin and also the probable intermediates involved have been discussed by Fawcett (1961). Indolylacetic acid has also been implicated in tumour formation in plants and this aspect has been reviewed by Braun (1962). The hyperauxinic condition of tomato crown-gal...

The study investigates the cellular expression of kynurenine aminotransferases (KAT I and II) in the rat retina during development. At P1 (the day of birth) and P7 (the 7th day after birth), KAT I expression was observed in the inner plexiform layer (IPL), the fiber layer (FL), and in vertically running processes in the ganglion cell layer (GCL) (but not in the cell bodies). At P14 (the 14th da...