Acute myelogenous leukemia (AML) is a hematological malignancy, which accounts for about 15-25% of childhood's leukemia. Genetic factor is one of the most important predisposing elements in childhood acute leukemia, especially AML. In this case report, a rare presentation of familial AML is presented in three monozygotic triplets. Two were 10 months old, and the other one was 16 months old at p...

intoduction: acute myeloid leukemia (aml) is a heterogeneous group of hematologic malignancies with abundant changeability in the pathogenesis. dna methylation of cpg islands within the promoters of specific genes may play roles in tumor initiation and progression. secreted frizzled-related proteins (sfrps) are negative regulator of the wnt signaling pathway. in the present study, we examined t...

Background: Acute leukemias comprise a heterogeneous group of diseases characterized by rapid and uncontrolled clonal expansion of progenitor cells of the hematopoietic system. Immunophenotyping helps subclassify acute leukemias into subgroups with prognostic implications. Materials and Methods: This descriptive observational cross-sectional study was performed on 80 newly diagnosed cases of a...

Differentiation Syndrome (DS) has been identified in a subset of patients undergoing treatment with novel classes differentiating therapies for acute myeloid leukemia (AML) such as IDH and FLT3 inhibitors. While DS is well-known treatment-related complication promyelocytic (APL), efforts are still ongoing to standardize diagnostic parameters AML. Though the rates incidence vary, many signs symp...

BACKGROUND AND OBJECTIVE Due to the increasing demand for aesthetic procedures, especially facial aesthetic surgery, a new laser technology has been developed for facial skin rejuvenation and wrinkle treatment. The aim of this study was to objectively and subjectively assess the clinical efficacy and safety of Erbium:YAG laser combined with Spatially Modulated Ablation (Er:YAG + SMA) on facial ...

granulocytic sarcomas (chloromas) are rare extramedullary tumors consisting of primitive granulocytic cells. we report here on a case of a 23-year-old man who presented with a generalized swelling. he is known case of acute myelomonocytic leukemia. granulocytic sarcomas are rare, destructive, extramedullary tumor masses that consist of immature granulocytic cells. in this unusual patient's case...

We have found the solution to the back reaction of putting a stack of coincident D3 and D5 branes in R×M6, where M6 is constructed from an infinite class of Sasaki-Einstein spaces, L. The non-zero fluxes associated to 2 and 3-form suggests the presence of non-contractible 2 and 3-cycles in this geometry. The radial part of the warp factor has the usual form and possess the cascading feature. We...

Background: Acute myeloid leukemia (AML) is one of myeloid malignancies which the risk increases with age increment. It is categorized based on genetic aberrations. Some of these genetic disorders can determine minimal residual diseases (MRD) and prognosis of AML patients. Wilms tumor (WT1) over expression is found in AML patients. The aim of this study was to determine the frequency of WT1 ove...

ABSTRACT Three patients were diagnosed at our facility with therapy-related acute myeloid leukemia (t-AML) but had differing etiologies. Patient A was a 30-year-old male history of lymphoblastic in remission. The patient admitted to the hospital early 2019 for pain control and concurrent pancytopenia. bone marrow biopsy performed because concern relapsed disease. showed 96.6% blasts 95...

Acute myeloid leukemia (AML-M7) is a type of pediatric AML accounting for 3–10% of primary childhood AML and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions. We report a rare case of AML .A 26-month-old boy who presented with weakness and fatigue. He was diagnosed as a case of AMLM-7...