نتایج جستجو برای: ammine complex
تعداد نتایج: 784001 فیلتر نتایج به سال:
In this paper, the mer-Co(NH3)3(NO2)3 complex was used as a new precursor for synthesizing spinel-type cobalt oxide nanoparticles (Co3O4NPs).Thermal decomposition of the complex at low temperature (175 °C) resulted in the Co3O4NPs without using expensive and toxic solvents or complicated equipment. XRD, FT-IR, SEM, EDX, and TEM were employed to characterize the product, and its optical and magn...
The cytotoxicity of a novel platinum(IV) complex, bis-acetato-amminedichloro-cyclohexylamine platinum(IV) (JM216), has been evaluated in vitro against a panel of human tumor cell lines (predominantly ovarian) representative of models of intrinsic and acquired to cisplatin. In addition, the activity of JM216 administered by the p.o. route has been determined in vivo using the murine ADJ/PC6 plas...
Using a panel of six human ovarian carcinoma cell lines varying by two orders of magnitude in terms of cisplatin cytotoxicity, we have investigated the in vitro antitumor activity of a series of novel alkylamine ammine dicarboxylatodichloroplatinum(IV) complexes of the general formula c,t,c-[PtCl2(OCOR1)2NH3(RNH2)]. A clear relationship existed between increasing the number of carbons in the R1...
Intrinsic resistance to existing clinical platinum drugs is a major cause of treatment failure; moreover, these agents have the drawbacks of cross-resistance and intravenous administration. The mechanism of intrinsic cisplatin resistance and the mechanism of circumvention of intrinsic resistance by a member (JM221) of the ammine/amine platinum (IV) dicarboxylate class of platinum complex was st...
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