نتایج جستجو برای: amphotericin
تعداد نتایج: 7081 فیلتر نتایج به سال:
A new triazole, Bay R 3783, was compared with ketoconazole, itraconazole, and fluconazole, which were given via the alimentary tract at three dosages, and amphotericin B, which was given at 1 mg/kg intraperitoneally, in murine models of the systemic mycoses coccidioidomycosis, histoplasmosis, and blastomycosis. In a pulmonary coccidioidomycosis model, Bay R 3783, fluconazole, and itraconazole w...
BACKGROUND Patients with neutropenia and persistent fever are often treated empirically with amphotericin B or liposomal amphotericin B to prevent invasive fungal infections. Antifungal triazoles offer a potentially safer and effective alternative. METHODS In a randomized, international, multicenter trial, we compared voriconazole, a new second-generation triazole, with liposomal amphotericin...
BACKGROUND Amphotericin B dexoycholate is currently the standard empirical antifungal therapy for neutropenic patients with hematologic malignancies and who also have persistent fever that does not respond to antibacterial therapy. The antifungal triazoles offer a potentially safer and effective treatment alternative to Amphotericin B dexoycholate. METHODS We assessed the efficacy and safety ...
Effect of Nigella Sativa Extract on Renal Functions in Amphotericin B Induced Nephrotoxicity in Mice
Introduction: Amphotericin B is considered as one of the most effective antifungal drugs presently used to treat systemic fungal infections; however, nephrotoxicity remains the major side effect. The current study is therefore, designed to determine Amphotericin B induced nephrotoxicity and its prevention by administration of Nigella sativa (NS) extract in albino mice. Materials and Methods: Th...
The clinically used antifungal polyene amphotericin B was conjugated, via the mycosamine and aglycon moieties, to fluorophores.
introduction invasive mucormycosis is an opportunistic fungal infection in patients with predisposing factors. case presentation we report a case of sino-orbito-cerebral mucormycosis in a diabetic patient successfully treated with combination of liposomal amphotericin b (l-amb) and posaconazole. conclusions clinicians should be alert of the clinical presentation of this fulminant fungal infecti...
background: orbital mucormycosis caused by zygomycetes is a rare and fatal infection that generally affects the patients who are immunocompromised. despite antifungal therapy and aggressive surgical intervention, mucormycosis can cause serious and rapidly fatal infections if delayed diagnosis or therapeutic management occurs. here, we report orbital mucormycosis in a healthy boy, wit...
The in vitro activity of thimerosal versus those of amphotericin B and natamycin was assessed against 244 ocular fungal isolates. The activity of thimerosal against Fusarium spp., Aspergillus spp., and Alternaria alternata was 256 times, 512 times, and 128 times, respectively, greater than that of natamycin and 64 times, 32 times, and 32 times, respectively, greater than that of amphotericin B....
We evaluated the efficacies of posaconazole and voriconazole in comparison with that of amphotericin B in a systemic murine infection by Candida krusei. Posaconazole at 50 mg/kg/day and voriconazole at 40 and 60 mg/kg/day prolonged survival and reduced the fungal tissue burden in the kidneys of mice similarly to amphotericin B at 1.5 mg/kg/day and liposomal amphotericin B at 10 mg/kg/day. None ...
background: invasive fungal infections (ifis) are chief infectious complications in patients undergoing hematopoietic stem cell transplantation (hsct). however, the diagnosis of fungal infections is difficult, and often empiric treatment initiates. since there is no data available on the prevalence of antifungal drugs administration in allogeneic hsct recipients in iran, we decided to conduct t...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید