نتایج جستجو برای: ampullary tumor

تعداد نتایج: 428904  

Journal: :Cancer cell 2016
Shinichi Yachida Laura D Wood Masami Suzuki Erina Takai Yasushi Totoki Mamoru Kato Claudio Luchini Yasuhito Arai Hiromi Nakamura Natsuko Hama Asmaa Elzawahry Fumie Hosoda Tomoki Shirota Nobuhiko Morimoto Kunio Hori Jun Funazaki Hikaru Tanaka Chigusa Morizane Takuji Okusaka Satoshi Nara Kazuaki Shimada Nobuyoshi Hiraoka Hirokazu Taniguchi Ryota Higuchi Minoru Oshima Keiichi Okano Seiko Hirono Masamichi Mizuma Koji Arihiro Masakazu Yamamoto Michiaki Unno Hiroki Yamaue Matthew J Weiss Christopher L Wolfgang Toru Furukawa Hitoshi Nakagama Bert Vogelstein Tohru Kiyono Ralph H Hruban Tatsuhiro Shibata

Ampullary carcinomas are highly malignant neoplasms that can have either intestinal or pancreatobiliary differentiation. To characterize somatic alterations in ampullary carcinomas, we performed whole-exome sequencing and DNA copy-number analysis on 60 ampullary carcinomas resected from clinically well-characterized Japanese and American patients. We next selected 92 genes and performed targete...

Journal: :Annals of clinical and laboratory science 1974
A M Lawrence E Paloyan

Newer laboratory aids complement evaluation of a patient with suspect pancreatic tumor, pancreatic adenocarcinoma, pseudocyst of the pancreas and islet cell adenoma. Hypertonic duodenography, artériographie study of the celiac trunk and superior mesenteric tree when combined may yield invaluable diagnostic information in patients with ampullary carcinoma. The new tech­ niques of transduodenal v...

2011
Timothy C. Tricas Bruce A. Carlson

Many animals have the ability to detect electric and magnetic fields. Although many species respond and orient to magnetic stimuli, only recently were putative vertebrate receptor systems identified. All organisms generate weak electric fields in water, due to an uneven distribution of ions between the interior of the organism and the external aqueous environment. Ampullary electroreceptors are...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1997
J R Howe D S Klimstra C Cordon-Cardo P B Paty P Y Park M F Brennan

The role of K-ras mutations in the progression of tumors of the ampulla of Vater is not well understood. To study the frequency and timing of K-ras mutations in ampullary tumors, areas of invasive carcinoma and adjacent adenomas were microdissected from paraffin blocks from 96 resected tumors. DNA was extracted, PCR amplification of K-ras exon 1 was performed, and PCR products were sequenced. S...

2005
David S. Klimstra Carlos Cordon-Cardo Philip B. Paty Patrick Y. Park Murray F. Brennan

The role of K-ras mutations in the progression of tumors of the ampulla of Vater is not well understood. To study the frequency and timing of K-ras mutations in ampullary tumors, areas of invasive carcinoma and adjacent adenomas were microdissected from paraffin blocks from 96 resected tumors. DNA was extracted, PCR amplification of K-ras exon 1 was performed, and PCR products were sequenced. S...

Journal: :JOP : Journal of the pancreas 2011
Ignasi Poves Fernando Burdio Sandra Alonso Agustín Seoane Luís Grande

CONTEXT Primary adenocarcinoma of the duodenum is a rare digestive malignancy which is commonly treated by radical surgical resection, pancreaticoduodenectomy being the technique of choice. Complete tumor resection obtaining free margins should be the standard of treatment for primary adenocarcinoma of the duodenum. Segmental duodenal resection is an appropriate operation for selected cases of ...

Journal: :Collegium antropologicum 2006
Darko Jurisić Marko Doko Elizabet Glavan Damir Rosko Dinko Vidović Karla Tomić

Worldwide there is no general attitude on optimal surgical procedure in treatment of primary non-ampullary adenocarcinoma of duodenum, especially for early stage of duodenal cancer. Some authors prefer local excision and segmental resection while others rather perform duodenopancreatic resection, even in the case of early stage of duodenal cancer with aim to avoid tumor recurrence. In this pape...

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