OBJECTIVE To determine preoperative ventricular function in vascular amputees by measuring N-terminal pro-brain natriuretic peptide (NT-proBNP) and to analyse the relationship between NT-proBNP levels and 30-day postoperative mortality. DESIGN Prospective pilot study. SUBJECTS AND METHODS In 19 patients planned for a lower limb amputation for non-reconstructable peripheral arterial disease ...

The prevalence of limb amputation is increasing globally as a devastating experience that can physically and psychologically affect the lifestyle of a person. The residual limb pain and phantom limb pain are common disabling sequelae after amputation surgery. Assistive devices/technologies can be used to relieve pain in people with amputation. The existing assistive devices/technologies for pai...

in this case report, it is our purpose to relate our findings concerning bloody discharge as an ominous sign in the conservative management of premature rupture of membranes, (prom) as well as to present relevant findings of the amniotic band syndrome such as amputation of one leg, constriction rings in two fingers, and pseudosyndactyly in the toes of the remaining foot in a 28 week old newborn...

Amputation of a segment of the tail produced long-lasting changes in nociception and morphine-induced antinociception. Plastic changes in nociceptive transmission may occur at the spinal cord as well as supraspinal structures after tail amputation. Acute hyperalgesia is detected at the remaining part of the tail as well as hindpaw. Morphine induced facilitation of the hot-plate (HP) response at...

OBJECTIVES To assess the trends of peripheral arterial disease associated major lower limb amputation in Hungary over a 9 year period (2004-2012) in the whole Hungarian population. METHODS This was a retrospective cohort study employing administrative health care data. Major amputations were identified in the entire Hungarian population during a 9 year period (2004-2012) using the health care...

BACKGROUND The objective of this paper is to describe and conceptualize an unusual and probably rare condition: the intense longstanding desire to have an amputation. METHOD Structured interviews were conducted by telephone of 52 subjects (mean age: 48.6, range 23-77 years; 47 male, 4 female, 1 intersexed) self-identified as having had a desire to have an amputation. RESULTS Seventeen per c...

A prospective, multicenter, cohort study from Italy December 2016 to 2018. For 287 patients with chronic limb-threatening ischemia (CLTI) who underwent open, endovascular, or hybrid lower extremity revascularization, the 30-day major adverse cardiovascular and limb events (MALE) rates were 3% 2%, respectively. At 1 year, overall survival, amputation-free freedom MALE, primary patency rate was 8...

BACKGROUND Health-related quality of life (HRQoL) is poor in patients with persistent diabetic foot ulcers and poor HRQoL predicts worse outcomes in these patients. Amputation is often considered a treatment failure, which is why conservative treatment is generally preferred over amputation. However, it is unclear whether minor amputation negatively affects HRQoL compared with conservative trea...

PURPOSE Complete fibula absence often presents with significant lower-limb deformity. Parental counselling regarding management is paramount in achieving the optimum functional outcome. Amputation offers a single surgical event with minimal complications. This study compares outcomes with an amputation protocol to those using an extension prosthesis. METHOD Thirty-two patients were identified...

OBJECTIVE To evaluate the reulceration and reamputation rates in a cohort of diabetic patients following first ray amputation. RESEARCH DESIGN AND METHODS We evaluated a cohort of 89 diabetic patients, 63 men and 26 women, who underwent first ray amputation in the period from January 2000 to December 2001. The first ray lesions were Wagner grade 2 in 3 patients, Wagner grade 3 in 47 patients,...