نتایج جستجو برای: amyloid disaggregation
تعداد نتایج: 39890 فیلتر نتایج به سال:
Electricity disaggregation focuses on identifying individual appliances from one or more aggregate signals. By reporting detailed appliance usage to consumers, disaggregation has the potential to significantly reduce electrical waste in residential and commercial sectors. However, application of existing methods is limited by two critical shortcomings. First, supervised learning methods implici...
In a recent paper by Sumita and Rieders (1990), a new algorithm has been developed for computing the ergodic probability vector for large Markov chains. Decomposing the state space into M lumps, the algorithm generates a sequence of replacement processes on individual lumps in such a way that in the limit the ergodic probability vector for a replacement process on one lump will be proportional ...
An important problem facing managers is how to enhance the credibility, or believability, of their earnings forecasts. In this paper, we experimentally test whether a characteristic of a management earnings forecast—namely, whether it is disaggregated—can affect its credibility. We also test whether disaggregation moderates the relation between managerial incentives and forecast credibility. Di...
Examples from the Murray–Darling basin in Australia are used to illustrate different methods of disaggregation of reconnaissance-scale maps. One approach for disaggregation revolves around the de-convolution of the soil–landscape paradigm elaborated during a soil survey. The descriptions of soil map units and block diagrams in a soil survey report detail soil–landscape relationships or soil top...
objective: to study the mechanisms involved in amyloid formation processes, we made a mammalian cell culture model of amylin aggregation and characterized its properties. materials and methods: amyloid fibrils were extracted from cho cells and binding affinity to thioflavin t and congo red was investigated. then the apple-green birefringence of extracted fibrils was detected under polarized li...
alzheimer’s disease (ad) is a neurodegenerative disorder and the most common form of dementia. almost 47 million people suffer from dementia worldwide. ad accounts for approximately 60%–80% of all dementia cases. three major pathologies characterize the disease: senile plaques, neurofibrillary tangles and inflammation. we review the literature on events contributing to the inflammation. those i...
Transgenic mice over-expressing mutant human amyloid precursor protein (PDAPP mouse) develop several Alzheimer’s disease (AD)-like lesions including an age-related accumulation of amyloid-?-containing neuritic plaques. Although aged, heterozygous PDAPP mice also exhibit synaptic and glial cell changes, that is characteristic of AD pathology, no evidence of neurodegeneration has been observed. T...
One-size-fits-all procedural safeguards are becoming increasingly suspect under the Due Process Clause. Although the precise requirements of due process vary from context to context, the Supreme Court has held that, within any particular context, the Due Process Clause merely requires one-size-fits-all procedures that are designed according to the needs of the average or typical person using th...
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