In this work, biphenyl and biphenyl oxide were extracted by direct single drop microextraction (direct-SDME) and analyzed by gas chromatography flame ionization detection. The extraction occurred by suspending a 7 μL drop of toluene (as extracting solvent) containing acetonaphton (as internal standard) from the tip of a microsyringe in direct-SDME, respectively. The effect of different paramete...

Forty-one chiral sulfoxides and sulfinate esters were separated using sulfated beta-cyclodextrin and carboxymethyl beta-cyclodextrin as chiral selectors. Binding constants of some analytes to both chiral selectors were measured in order to examine and help explain the observed migration behavior and enantioselectivity trends. Overall, sulfated beta-cyclodextrin separated a greater number of com...

Ochratoxin A (OTA) is a type of mycotoxin generated from the metabolism of Aspergillus and Penicillium, and is extremely toxic to humans, livestock, and poultry. However, traditional assays for the detection of OTA are expensive and complicated. Other than OTA aptamer, OTA itself at high concentration can also adsorb on the surface of gold nanoparticles (AuNPs), and further inhibit AuNPs salt a...

An analytical method is presented here for the assessment of morphine and codeine concentrations in human serum by employing mass spectrometry in the selective ion monitoring mode following its separation with gas chromatography. Deuterated (marked with heavy water) analogies of the analytes were used as surrogate internal standards. Samples were cleaned up using solid phase extraction. The tar...

Optimization of sample pre-treatment. Complete removal of cellular and further solid sample constituents, precipitation and removal of proteins, precipitation and removal of cholesterol from the blood sample and quantitative extraction of the analytes tryptophan, phenol, p-cresol and cholic acid in the diluted blood plasma phase. Step III: Combination and conversion of both isocratic HPLC/DAD/M...