background: systemic lupus erythematosus (sle) is a chronic autoimmune disease which is characterized by b-cell abnormality and auto-antibody generation. since bacterial infections are the most important causes of mortality in these patients, pneumococcal vaccination is recommended for children with sle. objective: to investigate humoral immunity and specific-antibody formation in response to a...

neonatal tetanus (nt) is a leading cause of neonatal mortality in many parts of the world. tetanus is a vaccine-preventable disease and is second only to measles worldwide as a cause of childhood mortality. in this study the various irnrnunoglobulin classes of anti-tetanus antibody in the sera of 105 iranian women of childbearing age (13-45 years) were titrated by enzyme linked immunosorbent as...

objective(s):in the present study, we evaluated immunological and immunomodulatory properties of royal jelly (rj) in 2,4,6 trinitrobenzene sulfonic acid (tnbs)-induced colitis in rats. materials and methods: eighteen adult female wistar albino rats were divided into three groups of six animals each: a control group that received only saline solution, a tnbs-induced colitis group, and a tnbs-col...

We recently reported that cross-linking the leukocyte common antigen (CD45) can rapidly induce aggregation of human peripheral blood mononuclear cells via lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) interactions. Herein, we have examined both T-cell--monocyte cellular interactions and the molecular signaling that are involved in this phenomeno...

The decidua basalis of developing mouse implantation sites is highly enriched in CD45+ leukocytes. In intact, syngeneically mated C57BL/6 decidua basalis examined at gestation day 8.5 by whole-mount in situ immunohistochemistry, leukocyte, but not trophoblast, conjugations were reported. Nothing is known regarding time course, frequency, composition, or importance of physiologic decidual CD45+ ...

Neonatal tetanus (NT) is a leading cause of neonatal mortality in many parts of the world. Tetanus is a vaccine-preventable disease and is second only to measles worldwide as a cause of childhood mortality. In this study the various irnrnunoglobulin classes of anti-tetanus antibody in the sera of 105 Iranian women of childbearing age (13-45 years) were titrated by enzyme linked immunosorben...

Objective(s):In the present study, we evaluated immunological and immunomodulatory properties of royal jelly (RJ) in 2,4,6 trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. Materials and Methods: Eighteen adult female Wistar albino rats were divided into three groups of six animals each: a control group that received only saline solution, a TNBS-induced colitis group, and a TNBS-co...

Background: Infection is now the most common cause of morbidity in Systemic Lupus Erythematosus (SLE). There is lack of information regarding the specific antibody forma-tion in response to vaccines in young SLE patients. Objective: To determine the efficacy of anti-tetanus antibody response in young patients with SLE. Methods: Forty SLE pa-tients with mean age of 14.1 years (range: 7-21) and 6...