Adaptogens were initially defined as substances that enhance the "state of nonspecific resistance" in stress, a physiological condition that is linked with various disorders of the neuroendocrine-immune system. Studies on animals and isolated neuronal cells have revealed that adaptogens exhibit neuroprotective, anti-fatigue, antidepressive, anxiolytic, nootropic and CNS stimulating activity. In...

OBJECTIVES Sub-health has been described as a chronic condition of unexplained deteriorated physiological function, which falls between health and illness. In the present study, we evaluated the effects of Lycium barbarum polysaccharide (LBP), a polysaccharide fraction purified from Lycium barbarum (L. barbarum) on the sub-health mice. MATERIALS AND METHODS The sub-health model mice were buil...

driver fatigue may impose the risk of crashes and is a leading cause of death in transportation industry. this study aimed to detect driver cognitive fatigue based on changes in eeg frequency bands in non-professional drivers during a simulated driving task. in a descriptive-analytical study, 12 healthy male car drivers took part in a two hour driving session on a simulated monotonous road, whi...

The in vitro antioxidant activity and in vivo anti-fatigue activity of loach peptide (LP) were determined. Results showed that LP contained the amino acids, which were expected to contribute to its antioxidant and anti-fatigue activities. LP could scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) (IC50 17.0 ± 0.54 mg/ ml) and hydroxyl radicals (IC50 2.64 ± 0.29 mg/ml). It could chelate cupric ion a...

ABSTRACT Introduction: Fatigue is a manifestation of sub-health status, which causes serious negative effects in daily life. The antioxidant properties crocin have been widely investigated many diseases. However, no correlation between and fatigue was reported. Objective: To verify the anti-fatigue efficacy swimming-induced exhaustive time. Materials Methods: In this study, mice were treated wi...

Deer antler is a well-known traditional Chinese medicine used in Asian countries for the tonic and the improvement of aging symptoms. The present study was designed to investigate the antifatigue effect and mechanism of Formosan sambar deer tip antler extract (FSDTAE). The swimming times to exhaustion of mice administered FSDTAE (8.2 mg/day) for 28 days were apparently longer than those of the ...

OBJECTIVE To evaluate the effectiveness of a modified Myers' formula of intravenous nutrient therapy (IVNT) on the symptoms of fibromyalgia (FM) in therapy-resistant FM patients. METHODS In this pilot clinical trial, 7 participants with therapy resistant FM were given IVNT once per week for 8 weeks. Patient's pain levels, fatigue, and activities of daily living were evaluated weekly. RESULT...

First-principles calculations based on density functional theory have been performed for the quaternary GaAs1-x-y N x Bi y alloy lattice-matched to GaAs. Using the state-of-the-art computational method with the Heyd-Scuseria-Ernzerhof (HSE) hybrid functional, electronic, and optical properties were obtained, including band structures, density of states (DOSs), dielectric function, absorption co...

The purpose of this study was to: a) identify changes in jump height and perceived well-being as indirect markers of fatigue, b) determine the internal and external workloads performed by players, and c) examine the influence of Yo-Yo IR2 on changes in jump height, perceived well-being and internal and external workloads during a tag football tournament. Microtechnology devices combined with he...

Curcumin (CCM) is a well-known phytocompound and food component found in the spice turmeric and has multifunctional bioactivities. However, few studies have examined its effects on exercise performance and physical fatigue. We aimed to evaluate the potential beneficial effects of CCM supplementation on fatigue and ergogenic function following physical challenge in mice. Male ICR mice were divid...