The present study is carried out for the evaluation of anti-HIV-1 effect of Dimocarpus longan extracts and also the investigation of the phytoconstituents from the extracts. Chloroform, ethyl acetate and methanol 80% extracts of Dimocarpus longan aerial parts were tested for their antiHIV-1 activity using the syncytia formation assay. Ethyl acetate from Dimocarpus longan aerial parts extract ha...

Anti-retroviral therapy (ART) is crucial for controlling human immunodeficiency virus type-1 (HIV-1) infection. Recently, progress in identifying and characterizing highly potent broadly neutralizing antibodies has provided valuable templates for HIV-1 therapy and vaccine design. Nevertheless, HIV-1, like many RNA viruses, exhibits genetically diverse populations known as quasispecies. Evolutio...

in western asia, afghan refugees constitute one of the main vulnerable populations with drug and hiv treatment needs. however, there is not considerable provision of drug and hiv services for this group. the study aimed to describe the provision of drug treatment and harm reduction services for afghan refugees in iran, the most populous persian gulf country. with the collaboration of the united...

conclusions: it can be concluded that cognitive-behavioral and spiritual training was effective for the improvement of mental health of hiv positive drug addicts. results: the result of the present research showed that cognitive-behavioral trainings with an emphasis on spirituality were effective for improving quality of life, regarding general aspects of mental and physical health, sub-scales ...

There are currently a number of antiretroviral drugs that have been approved by the Food and Drug Administration for use in the treatment of human immunodeficiency virus (HIV). More recently, antiretrovirals are being evaluated in the clinic for prevention of HIV infection. Due to the challenging nature of treatment and prevention of this disease, the use of nanocarriers to achieve more efficie...

Although a number of anti HIV drugs have been approved, there are still problems with toxicity and drug resistance. This demonstrates a need to identify new compounds that can inhibit infection by the common drug resistant HIV-1 strains with minimal toxicity. Here we describe an efficient assay that can be used to rapidly determine the cellular cytotoxicity and efficacy of a compound against WT...

From the trends of human immunodeficiency virus (HIV) epidemics in South and Southeast Asia, it was postulated that an HIV epidemic would start as a bloodborne infection among injecting drug users in the Philippines. In 2002, 560 individuals were recruited in Metro Cebu, Philippines and tested for HIV, hepatitis C virus (HCV) and hepatitis B virus (HBV) infections. Seroprevalence of anti-HCV am...

Background. Increasing incidences of HCV infection in MSM with HIV infections were reported in the United States and Europe. However, there are few studies regarding the epidemiology of HCV in HIV infected patients in Asian countries. Methods. To determine the risk factors of HCV infection, and the incidence of HCV in in HIV infected patients, a retrospective cohort study was performed. All HIV...

From the trends of human immunodeficiency virus (HIV) epidemics in South and Southeast Asia, it was postulated that an HIV epidemic would start as a blood-borne infection among injecting-drug users in the Philippines. In 2002, 560 individuals were recruited in Metro Cebu, Philippines and tested for HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV) infections. The seroprevalence of anti-...