Herb-drug interaction (HDI) limits clinical application of herbs and drugs, and inhibition of herbs towards uridine diphosphate (UDP)-glucuronosyltransferases (UGTs) has gained attention as one of the important reasons to cause HDIs. Sauchinone, an active lignan isolated from aerial parts of Saururus chinensis (Saururacease), possesses anti-oxidant, anti-inflammatory, and anti-viral activities....

burns are known as one of the most common forms of injury with devastating consequences. despite the discovery of several antiseptics, burn wound healing has still remained a challenge to modern medicine. herbal products seem to possess moderate efficacy with no or less toxicity and are less expensive compared to synthetic drugs. burn is a well-known disorder in iranian traditional medicine (it...

Spices and herbs have been used in traditional medicine for centuries, with research starting to accumulate on their beneficial properties. Of these properties, the immune-enhancing anti-inflammatory capabilities of many spices led promising results. The current review article aims explore several as immune-enhancers agents. examined are African potato (Hypoxis hemerocallidea), allspice (Piment...

OBJECTIVE(S) In the current study, the effects of selected folk medicinal herbs were evaluated in D-galactose-induced aging in male mice. MATERIALS AND METHODS Male BALB/c mice were randomly divided into 12 groups composing sham, control, and treated groups. Aging was induced by administration of D-galactose (500 mg/kg/day for 6 weeks). A positive control group was assigned that received vita...

Anxiety is a prominent indication for herbal medicine. This systematic review was therefore aimed at summarising the evidence for or against the anxiolytic efficacy of such treatments. Six databases were searched for all randomised clinical trials testing herbal monopreparations in the alleviation of anxiety. Seven such studies and one systematic review were located. Eight different herbals wer...

Targeted cancer therapies, with specific molecular targets, ameliorate the side effect issue of radiation and chemotherapy and also point to the development of personalized medicine. Combination of drugs targeting multiple pathways of carcinogenesis is potentially more fruitful. Traditional Chinese medicine (TCM) has been tailoring herbal mixtures for individualized healthcare for two thousand ...