نتایج جستجو برای: anti tetanus antibody

تعداد نتایج: 483861  

Journal: :The Journal of clinical investigation 1982
F Gigliotti R A Insel

Postimmunization human B lymphocytes and mouse myeloma cells were fused to produce interspecies hybridomas secreting human antibody of predefined specificity with an initial frequency comparable to intraspecies fusion. After 13 mo in culture, one clone continued to secrete high titers of human IgG antitetanus toxin antibody. This antibody binds to the B fragment of tetanus toxin and protects mi...

2015
Anthony Shock Linda Burkly Ian Wakefield Christopher Peters Ellen Garber Janine Ferrant Frederick R. Taylor Lihe Su Yen-Ming Hsu David Hutto Ali Amirkhosravi Todd Meyer John Francis Sarah Malcolm Martyn Robinson Derek Brown Stevan Shaw Roland Foulkes Alastair Lawson Olivier Harari Timothy Bourne Alison Maloney Neil Weir

INTRODUCTION CD40 ligand (CD40L) blockade has demonstrated efficacy in experimental autoimmune models. However, clinical trials of hu5c8, an anti-human CD40L IgG1 antibody, in systemic lupus erythematosus (SLE) were halted due to an increased incidence of thrombotic events. This study evaluated CDP7657, a high affinity PEGylated monovalent Fab' anti-CD40L antibody fragment, to assess whether an...

Journal: :British medical journal 1976
H C Whittle A Oduloju G Evans-Jones B M Greenwood

Twenty-six patients who had recovered from group A meningococcal meningitis were vaccinated with group C meningococcal polysaccharide and tetanus toxoid. Their haemagglutinating antibody response was measured two weeks later and compared with those of 22 siblings and 39 controls. Patients and siblings had a significantly lower antibody response to the group C vaccine but not to tetanus toxoid. ...

Journal: :The Journal of clinical investigation 1983
J H Kehrl A S Fauci

The in vivo and in vitro immune response after in vivo immunization with pneumococcal polysaccharides (PPS) has been analyzed in man. Substantial differences were noted in this system when compared with human responses to soluble protein antigens. Within 6 d after immunization, specific PPS antigen-binding cells (ABC), specific plaque-forming cells (PFC), and cells capable of spontaneously synt...

Journal: :iranian journal of immunology 0
hasan shemirani faculty of medicine, isfahan university of medical sciences, isfahan, iran abbas rezaei faculty of medicine, isfahan university of medical sciences, isfahan, iran

background: myocardial infarction (mi) is one of the most common and serious diseases resulting from coronary artery occlusion and major reduction in blood flow. streptokinase as a thrombolytic is considered the first and most important therapeutic intervention for reperfusion following mi in most countries including iran. our previous study showed that, the prevalence of high antibody titers a...

Journal: :iranian journal of allergy, asthma and immunology 0
m. pour-amir m.j. rasaee m. ansari m. malekaneh and s. hadjizadeh

in this study we produced and purified a high titer of specific and high affin¬ity fab fragments of anti-digoxin antibody. immunization of rabbits with a conju¬gate of the cardiac glycoside digoxin, coupled by a periodate oxidation method to the amino group of lysine in bovine serum albumin resulted in the production of this type of high titer digoxin-specific antibodies with exceptionally high...

Journal: :international journal of hematology-oncology and stem cell research 0
mehrzad mirzania imam khomini hospital complex, vali-e-asr hospital, tehran university of medical sciences, tehran, iran. sedigheh khalili arak university of medical sciences, arak, iran. akbar hasanpoor arak university of medical sciences, arak, iran. ahmad reza shamshiri hematology-oncology and stem cell research center, tehran university of medical sciences, tehran, iran.

amegakaryocytic thrombocytopenia (amt) is a rare cause of acquired thrombocytopenia. the pathogenesis and treatment of amt is not clearly known. here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. the patient did not respond to intravenous immunoglob...

Journal: :journal of reproduction and infertility 0

background: anti-sperm antibody (asa) can decrease sperm motility and, therefore, it is a cause of male infertility. the aim of this study was to evaluate the effects of varicocelectomy on anti-sperm antibody in patients with varicocele. methods: this observational study was conducted on 90 patients with varicocele at sina and imam khomeini hospitals during 2006 to 2009. all varicocelectomy can...

2014
Ali Eslamifar Amitis Ramezani Mohammad Banifazl Masoomeh Sofian Fatemeh- Alsadat Mahdaviani Farhad Yaghmaie Arezoo Aghakhani

BACKGROUND AND OBJECTIVES Tetanus and diphtheria are vaccine-preventable, infectious diseases with significant morbidity and mortality. Immunization by the diphtheria and tetanus toxoid (DT) has been applied in Iran for almost 50 years. However, there are very few data about the rate of immunity to these diseases in the adult population. the humoral immunity to tetanus and diphtheria among bloo...

Journal: :journal of research in medical sciences 0
maryam salehi abbas haghighat hassan salehi roya taleban marzieh salehi nader kalbasi

background: hepatitis b virus (hbv) fails to produce appropriate immune responses in some healthy individuals; thus, different strategies have been adopted to promote immune responses. the current study aimed at evaluating the efficacy of hbv vaccine coadministered with tetanus-diphtheria (td) vaccine compared with hbv vaccine in healthy individuals through measuring hepatitis b surface antibod...

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