Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction on S. aureus antibiotic susceptibility remains poorly understood. In this study, we utilize a panel of P. aeruginosa burn wound and cystic fibrosis (CF) lung isolates...

Mammary secretions of 913 quarters from 229 pregnant Holstein heifers were obtained aseptically to determine the prevalence of coagulase-negative Staphylococci isolated during periparturient period. Quarter samples were collected 14 to 10 days before expected parturition. Analysis of culture data indicated that 78.5% (717/913) of samples were negative, 20.5% (187/913) contained coagulase-negati...

Determination of the MIC, based on the activities of antibiotics against planktonic bacteria, is the standard assay for antibiotic susceptibility testing. Adherent bacterial populations (biofilms) present with an innate lack of antibiotic susceptibility not seen in the same bacteria grown as planktonic populations. The Calgary Biofilm Device (CBD) is described as a new technology for the rapid ...

BACKGROUND An open observational study was performed to investigate changes in the rectal flora and antibiotic susceptibility among faecal bacteria in patients treated with antibiotics for acute intra-abdominal infection. METHODS One hundred and forty patients with acute intra-abdominal infection requiring antibiotic treatment and hospitalization were included. Eight surgical units from the s...

There is a rapid increase in the emergence of multidrug resistance which consider as one public health threats all over world. MDR was defined acquired non-susceptibility to at least agent three or more antimicrobial categories. The present study aims determine dominant multi-drug resistant bacteria five biggest hospitals Asir region, Saudi Arabia. Antibiotic-resistant isolates were collected f...

BACKGROUND Early administration of appropriate antibiotic therapy in bacteraemia patients dramatically reduces mortality. A new method for RApid Molecular Antibiotic Susceptibility Testing (RAMAST) that can be applied directly to positive blood cultures was developed and evaluated. METHODOLOGY/PRINCIPAL FINDINGS Growth curves and antibiotic susceptibility of blood culture isolates (Staphyloco...

There is a growing concern by regulatory authorities for the selection of antibiotic resistance caused by the use of biocidal products. We aimed to complete the detailed information on large surveys by investigating the relationship between biocide and antibiotic susceptibility profiles of a large number of Staphylococcus aureus isolates using four biocides and antibiotics commonly used in clin...