an identification of the environmental factors regulating the biosynthesis of antibiotics by fluorescent pseudomonads is an essential step toward improving the ability of these bacteria to control plant pathogens. investigation of nine fluorescent pseudomonads, utilized in growth suppression of rhizoctonia solani, the causal agent of root rot and damping-off of bean plants, by the method of hpl...

1 Shahab L, Jarvis MJ, Britton J, et al. Prevalence, diagnosis and relation to tobacco dependence of chronic obstructive pulmonary disease in a nationally representative population sample. Thorax 2006;61:1043–7. 2 Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive lung disease, www.goldcopd.com (accessed 18...

A decade of research has led to more precise guidelines for a complex health problem t has long been considered that all patients with heart conditions that predispose to infective endocarditis should receive antibiotic prophylaxis when undergoing procedures that can lead to bacteraemia with organisms known to cause endocarditis. However, the evidence for such action is surprisingly poor. 1 It ...

background: human exposure to antibiotic resistant bacteria (arb) is a public health concern which could occur in a number of ways. wastewaters seem to play an important role in the dissemination of bacteria and antibiotic resistant genes (args) in our environment. the aim of this study was to evaluate the occurrence of three groups of arb and their resistance genes in hospital and municipal wa...

BACKGROUND Estimating the risk of antibiotic resistance is important in selecting empiric antibiotics. We asked how the timing, number of courses, and duration of antibiotic therapy in the previous 3 months affected antibiotic resistance in isolates causing invasive pneumococcal disease (IPD). METHODS We conducted prospective surveillance for IPD in Toronto, Canada, from 2002 to 2011. Antimic...

BACKGROUND AND OBJECTIVE Single-center evaluations of pediatric antimicrobial stewardship programs (ASPs) suggest that ASPs are effective in reducing and improving antibiotic prescribing, but studies are limited. Our objective was to compare antibiotic prescribing rates in a group of pediatric hospitals with formalized ASPs (ASP+) to a group of concurrent control hospitals without formalized st...

The sexually transmitted bacterium Neisseria gonorrhoeae has developed resistance to all antibiotic classes that have been used for treatment and strains resistant to multiple antibiotic classes have evolved. In many countries, there is only one antibiotic remaining for empirical N. gonorrhoeae treatment, and antibiotic management to counteract resistance spread is urgently needed. Understandin...

Appendicectomy has been the gold standard treatment of acute appendicitis for more than a century, while nonoperative therapies, including antibiotics, have acquired increased interest in recent years. The present meta-analysis aimed to compare the therapeutic effects of antibiotics versus appendicectomy for the treatment of acute appendicitis. Medline, Embase and The Cochrane Library databases...