نتایج جستجو برای: anticancer agent

تعداد نتایج: 284103  

Journal: :Anticancer research 2016
Xiaoyuan Ma Y I Wu Xuewei Yang Shuang Yang Yuhuan Li Yushen Huang Robert J Lee Tian Bai Yungang Luo

AIM We screened nine 1,2-dihydro-quinolines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cytotoxicity assay in HepG2 and SMMC cells and identified ethyl-2-cyano-2-(2- (methoxycarbonyl)allyl)quinoline-1(2H)-carboxylate (compound 5) as a potential anticancer agent. In order to further develop its anticancer therapeutic potential, we incorporated this agent into cat...

Journal: :journal of physical & theoretical chemistry 2010
f. najafi l. saedi f. mollaamin h. aghaie

in this work, we have studied the solvent effects on values of gibbs free energy, enthalpy. entropy and dipolemoment in spread of solvents around anticancer thug of temreolomide that is an alighting agent. for thispurpose, the quantum mechanic calculations bawd on hanrertnick theory at the sto-36/3-2ith levels havebeen done. moreover, we have compared resulted thermodynamic values in gas phase ...

Journal: :Experimental oncology 2007
O I Dasyukevich G I Solyanik

AIM To study anticancer activity of conitine-containing agent BC1 in vivo. METHODS BC1 water solution was administered per os to mice bearing ascite or solid form of Ehrlich's carcinoma. Anticancer effect of BC1 administered per os was evaluated by the indexes of tumor growth inhibition and average life span of experimental animals. RESULTS BC1 didn't show anticancer activity in the case of...

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