background: toxoplasmosis is one of the prevalent parasitic diseases in the world with 10-40 percent of people having it as a latent infection. in cases of renal transplants, the condition either presents itself as a result of reactivation of the latent infection resulting in the weakness of immune system in a recipient or happens when a recipient simply contracts the condition from the donor t...

Splanchnic vein thrombosis (SVT) refers to Budd-Chiari syndrome (BCS) and portal vein system thrombosis (PVST). Current practice guidelines have recommended the routine screening for antiphospholipid antibodies (APAs) in patients with SVT. A systematic review and meta-analysis of observational studies was performed to explore the association between APAs and SVT. The PubMed, EMBASE, and Science...

Sốt xuất huyết Dengue là một bệnh truyền nhiễm cấp tính do virus gây ra, lây qua muỗi Aedes. Nghiên cứu này đánh giá số đặc điểm học, chức năng gan, kháng thể ở 253 nhân (BN) sốt Dengue. Kết quả nghiên cho thấy chỉ anti-DENV-IgM, anti-DENV-IgG thay đổi rõ rệt giữa nhóm (DF) và có dấu hiệu cảnh báo (DWS) (p<0,05). Có mối liên quan tăng hoạt độ ALT AST, giảm lượng tiểu cầu DF hoặc anti-DENV-Ig...

  Introduction : Human cytomegalovirus (HCMV) is able to go into latency and is the most common cause of congenital infections in humans. Its clinical manifestations range from asymptomatic forms to severe fetal damage, and in rare cases, fetal death due to abortion. This prospective cross-sectional study was designed to determine the seroprevalence of HCMV infection in pregnant women attending...

background: toxoplasma specific igm antibodies; the common serologic marker in diagnosis of acute toxoplasmosis has its own limitations. confirmatory testing with other markers, introduced as a complementary tool in distinguish acute and chronic infections is unusual in iran. in the present study, we investigated the cor-relation between the results of igm elisa, iga elisa, and igg avidity test...

The antiphospholipid syndrome (APS) is defined by the association of arterial and/or venous thrombosis and/or pregnancy complications with the presence of at least one among the main antiphospholipid antibodies (aPL) (i. e., Lupus anticoagulants, LA, IgG and/ or IgM anticardiolipin antibodies, aCL, IgG and/or IgM antiβ2-glycoprotein I antibodies, aβ2-GPI). Several clinical studies have consiste...

A possible co-appearance of anticardiolipin (aCL), anti-β2-glycoprotein I (anti-β2-GPI), anti-prothrombin (aPT) and anti-annexin V (aANXV) antibodies of IgG, IgM and IgA class were studied in 58 patients with SLE alone and 32 patients APS in the view of rational laboratory diagnostics. The presence of anti-phospholipid antibodies (aPL) were defined by our in-house ELISA methods. Out of 17 aCL n...

To cite: Parchand SM, Vijitha VS, Misra DP. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016218848 DESCRIPTION A girl aged 16 years presented with sudden loss of vision in the left eye (LE) for 1 day. Visual acuity was 6/6 in the right eye (RE) and perception of light in LE. LE had relative afferent pupillary defect. RE fundus had cotton wool spots (figure 1A)...

The lack of reliable standardization tools as well as the poorly defined nature of the "Cardiolipin antigen" makes the development of the anticardiolipin antibody (ACA) assays (for anti-IgG and IgM detection) highly challenging. This article describes how several issues have been solved during the development of an automated ACA immunoassays, based on a technology that includes paramagnetic mic...