A 5.4-kDa antifungal peptide, with an N-terminal sequence highly homologous to defensins and inhibitory activity against Mycosphaerella arachidicola (IC(50)= 3 μM), Setospaeria turcica and Bipolaris maydis, was isolated from the seeds of Phaseolus vulgaris cv. brown kidney bean. The peptide was purified by employing a protocol that entailed adsorption on Affi-gel blue gel and Mono S and finally...

Objective (s): The green synthesis of copper nanoparticles using metabolites of microorganisms has gained much interest in recent years. In this work, it was studied optimization of copper nanoparticles synthesis using E. coli and its antifungal activity.Materials and Methods: The copper nanoparticles were synthesized by Escherichia coli. Effect of copper nitrate concentration and temperature w...

Catharanthus roseus is well known for its pharmacological significance. The present study aims to determine the antifungal activity of Catharanthus roseus against various clinically significant fungal strains (Candida albicans, Aspergillus fumigatus, Aspergillus niger, Fusarium moniliforme). Assessment of antifungal activity of Catharanthus roseus was done by paper disc diffusion method. In thi...

Crude extracts and fractions of five species of Polygala - P. campestris, P. cyparissias, P. paniculata, P. pulchella and P. sabulosa - were investigated for their in vitro antifungal activity against opportunistic Candida species, Cryptococcus gattii and Sporothrix schenckii with bioautographic and microdilution assays. In the bioautographic assays, the major extracts were active against the f...

bipolaris oryzae causes rice brown spot disease which reduces rice yield with substantial global impact. streptomycetes isolated from rice fields of guilan province, iran, showed antifungal activity against the tested pathogen. from five active streptomyces spp. isolates, isolate g showed high antagonistic activity. to determine its taxonomical identity, its colonies characterized morphological...

The aim of the study was investigate antifungal activity of the various leaves extracs of Achyranthes aspera Linn.The aqueous,ethanol and methanol leaves extracts of Achyranthes aspera Linn. (Family:Amaranthaceae) were evaluated for antifungal activity against clinically important fungal spp viz. Candida albicans (MTCC 227), C.tropicalis (MTCC 750), C.krusei (ATCC 6258), C.kefyr (ATCC 4235), C....

New tetrahydrocarbazole derivatives substituted at the heteroatom (N) by non-steroidal anti-inflammatory drug (NSAIDs) were synthesized reaction of cyclohehexanon (C.H.N.) with phenyl hydrazine (P.H.Z.) to form (THCZ), where latter is reacted NSAID (Ketoprofen) via amide bond yield
 THCZ, compounds chemical structures verified by: 1H, 13C NMR and FTIR spectroscopy.
 Antifungal activit...

In this study, we investigated the antifungal effects of silver nanoparticles (Ag-Nps) on Candida albicans (ATCC 5027), Saccharomyces cerevisiae (ATCC 5027). Investigating method by using Minimum Inhibitory Concentration (MIC) technique, some of drugs including Amphotericin B, Fluconazole and synthesized Ag-Nps have been obtained on the fungi and the changes on membrane reactions of yeasts have...

background. opportunistic fungal infections like candidiasis are common in the oral cavity. in recent years candida species have shown resistance against a number of synthetic drugs. this study assessed the antifungal activity of centratherum anthelminticum and ocimum sanctum seed oils against six common pathogenic candida strains. synergistic activity of the major oil components was also studi...