نتایج جستجو برای: antimalarial activity

تعداد نتایج: 1138771  

Journal: :Molecules 2016
Birgit Viira Thibault Gendron Don Antoine Lanfranchi Sandrine Cojean Dragos Horvath Gilles Marcou Alexandre Varnek Louis Maes Uko Maran Philippe M Loiseau Elisabeth Davioud-Charvet

Malaria is a parasitic tropical disease that kills around 600,000 patients every year. The emergence of resistant Plasmodium falciparum parasites to artemisinin-based combination therapies (ACTs) represents a significant public health threat, indicating the urgent need for new effective compounds to reverse ACT resistance and cure the disease. For this, extensive curation and homogenization of ...

Journal: :The Southeast Asian journal of tropical medicine and public health 2003
C Saiin R Rattanajak S Kamchonwongpaisan K Ingkaninan K Sukontason A Baramee B Sirithunyalug

The in vitro antimalarial activities against Plasmodium falciparum K1 of four extracts from the stembark of Picrasma javanica B1; ie water, methanol, chloroform and hexane extracts were studied using a modification of the [3H]hypoxanthine incorporation method. It was found that the hexane extract showed in vitro antimalarial activity with IC50 of 3.3 microg/ml. The extract was further fractiona...

Journal: :Asian Pacific Journal of Tropical Medicine 2014

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