It has been unclear to which antimicrobial activities (e.g., anti-gram-positive bacterial, anti-gram-negative bacterial, antifungal, antiparasitic, and antiviral activities) of antimicrobial peptides (AMPs) a given physiochemical property matters most. This is the first computational study using large-scale AMPs to examine the relationships between antimicrobial activities and two major physioc...

Based on the traditional usage, Moringa oleifera and Allamanda cathartica plants were selected. The present study is to find out its antimicrobial potential against clinical isolates of KMCHospital. The resistant patterns of the isolated pathogens were studied against commercial standard antibiotics. By using the different polar solvents (Methanol, Ethanol, Chloroform, Water, Petroleum ether an...

OBJECTIVE The present study was conducted to detect possible chemicals (phytoconstituents), prove ethno-medicinal value of the plant, and investigate antimicrobial, anthelmintic, and total phenolic content of crude methanolic extract of the Solanum violaceum plant. MATERIALS AND METHODS Phytochemical screening was carried out using different chemical group test methods. In anthelmintic activi...

The search for new substances with antimicrobial properties has become necessary due to the microbial capacity of resistance. Medicinal plants have become an important substitute since many plants exhibit antimicrobial activity. In this study, the ethanolic flower extracts of Punica granatum were assessed for their phytoconstituents and the antimicrobial property. A total of 21 microorganisms (...

OBJECTIVE In an attempt for better treatment of bacterial infections and burn wounds, plaster formulations containing different concentrations of norfloxacin were prepared using polymers like polyvinylpyrrolidone and polyvinyl alcohol and evaluated for physicochemical parameters, in vitro drug release, antimicrobial activity, and burn wound healing properties. The prepared formulations were com...

Chronic wounds are a major cause for both suffering and economical losses. Management of chronic non-healing wounds requires multipronged approach. They are polymicrobial and agonizing for the patient due to associated pain. Moist dressing providing antimicrobial action is a highly desirable chronic wound management option. Here we report a hydrogel based dressing that possesses the antimicrobi...

The antibacterial properties of nanoparticles (NPs) can be significantly enhanced by increasing the wettability or solubility of NPs in aqueous medium. In this study, we investigated the effects of the stabilizing agent on the solubility of silver NPs and its subsequent effect on their antimicrobial activities. Silver NPs were prepared using an aqueous solution of Pulicaria glutinosa plant extr...

Aim: The aim was to evaluate antimicrobial property of bacteriocin isolated from Escherichia coli against pathogenic bacteria from aquaculture sites. Materials and Methods: E. coli was isolated from fermented pineapple Ananas comosus using eosin methylene blue agar. The antimicrobial activity of the isolated E. coli was screened using hole-plate diffusion method. The bacterial strain that showe...

the major objective in endodontic therapy is to disinfect the entire root canal system. this requires that the pulpal content be eliminated as sources of infection. this goal may be accomplished by mechanical instrumentation and chemical irrigation, in conjunction with medication of the root canal between treatment sessions. microorganisms and their by-products are considered to be the major ca...

honey contains a wide variety of vitamins, minerals, amino acids and antioxidants. the vitamins found in honey include niacin, riboflavin and pantothenic acid; minerals present include calcium, copper, iron, magnesium, manganese, phosphorus, potassium and zinc. in addition honey contains a variety of flavonoids and phenolic acids which act as antioxidants, scavenging and eliminating free radica...