نتایج جستجو برای: antimycobacterial activity

تعداد نتایج: 1135098  

Journal: :Infection and immunity 1974
I Kochan C A Golden

Heptane-extractable fractions (HEF) prepared from immune-activated macrophages (IA-M) of tubercle bacilli or bovine gamma globulin-sensitized and -challenged guinea pigs inhibited the growth of tubercle bacilli whereas HEF of normal macrophages exerted no antibacterial activity. In distinction to the strong antibacterial activity of HEF of IA-M, HEF of immune macrophages exerted weak or no anti...

Journal: :Natural product communications 2015
Viviana Donoso Mitchell Bacho Solange Núiñez Juana Rovirosa Aurelio San-Martin Sergio Leiva

The present study was aimed at evaluating the antibacterial activity of mulinane and azorellane diterpenes isolated from the Andean plants Azorella compacta and A. trifoliolata and semisynthetic derivatives against reference and multidrug-resistant strains. The results revealed that the semisynthetic compound 7-acetoxy-mulin-9,12-diene (5) exhibited antibacterial activity against reference and ...

2014
Zhenjian Lin Michael Koch May Hamdy Abdel Aziz Rodrigo Galindo-Murillo Ma. Diarey Tianero Thomas E. Cheatham Louis R. Barrows Chris A. Reilly Eric W. Schmidt

A racemic, prenylated polyketide dimer, oxazinin A (1), was isolated from a novel filamentous fungus in the class Eurotiomycetes, and its structure was elucidated spectroscopically. The pentacyclic structure of oxazinin A (1) is a unique combination of benzoxazine, isoquinoline, and a pyran ring. Oxazinin A (1) exhibited antimycobacterial activity and modestly antagonized transient receptor pot...

Journal: :Antimicrobial agents and chemotherapy 2005
Irma A J M Bakker-Woudenberg Wim van Vianen Dick van Soolingen Henri A Verbrugh Michiel A van Agtmael

A number of antimycobacterial agents were evaluated with respect to their bacteriostatic activity (growth inhibition) versus the bactericidal activity against a clinical isolate of Mycobacterium avium (Mycobacterium avium complex [MAC] strain 101) in relation to the time of exposure and the growth phase of the mycobacteria. In terms of growth inhibition the MAC in the active phase of growth was...

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