A 47-year-old woman developed pulmonary hemorrhage and an increase in proteinuria during remission of membranous nephropathy. Renal biopsy revealed crescentic glomerulonephritis. She also had a high perinuclear antineutrophil cytoplasmic antibody level, so a diagnosis of myeloperoxidase-antineutrophil cytoplasmic antibody-associated glomerulonephritis was made. After immunosuppressive therapy w...

Wegener’s granulomatosis (WG) is a systemic vasculitic disease characterized by necrotizing granulomas and vasculitis of small vessels.1,2 Upper airway tract involvement is frequent over the course of the disease.1,3 Cytoplasmatic pattern antineutrophil cytoplasmic antibodies (c-ANCA) are highly specific for WG in the active phase.1,3 Proteinase 3-ANCA (PR3-ANCA) positivity is usually associate...

We report an interesting case of vasculitis in which the inflammatory lesion was limited to the peritracheobronchus. This case showed positive antineutrophil cytoplasmic antibodies, diffuse peritracheobronchial swelling, and vasculitis in its histology. Steroid therapy was effective for both roentgenological and serological findings. Although the biopsy specimen shows only inflammation and does...

We report a 13-year-old girl with acute pulmonary edema due to severe acute Mitral regurgitation because of rupture of Mitral valve ́s posteromedial papillary muscle. She had normal mitral valve with necrotic posteromedial papillary muscle, classic aneurysms in left coronary artery, neutrophilic infiltration in the wall of medium-sized vessel of kidney and positive perinuclear antineutrophil cyt...

A 39 year old woman with untreated coeliac disease presented with some of its complications and bilateral papillitis. She was found to have antineutrophil cytoplasmic antibodies (ANCA) in high titres. Following institution of gluten-free diet the complications resolved. The papillitis, however, persisted and needed a course of prednisolone to resolve, and a fall in the ANCA titres was noted. We...

On rare occasions, patients with Goodpasture’s syndrome (GPS) present both anti-glomerular basement membrane (GBM) and antineutrophil cytoplasmic antibody (ANCA). Concurrent ANCA anti-GBM disease is a high mortality rate. Here we case of (ANCA) complicated hyponatremia.