نتایج جستجو برای: antinociceptive activities

تعداد نتایج: 380840  

Journal: :Pharmacology Biochemistry and Behavior 2012
Humberto M. Spindola Débora B. Vendramini-Costa Manoel T. Rodrigues Mary A. Foglio Ronaldo A. Pilli João E. Carvalho

Harmicine is a β-carboline alkaloid isolated and identified as a major active compound present in many plant species and marine invertebrates. This alkaloid exhibits a wide spectrum of pharmacological activities, including antispasmodic, antipyretic, and anticancer properties. This report described the antinociceptive properties of harmicine by means of chemical experimental models in order to ...

2017
Niloofar Kahkeshani Milad Gharedaghi Abbas Hadjiakhoondi Mohammad Sharifzadeh Mahnaz Khanavi

OBJECTIVE The genus Marrubium is used for treatment of joint pain, gout, stomach-ache and colic in Iranian Traditional Medicine. Marrubium astracanicum Jacq. (M. astracanicum) is a native species in the flora of Iran. The aim of this study was to evaluate the antinociceptive properties of various extracts of aerial parts of M. astracanicum. MATERIALS AND METHODS Antinociceptive activities of ...

2015
Raxit P. Rachchh Varsha J. Galani

INTRODUCTION Grangea maderaspatana (L.) Poir. (Asteraceae), a popular Indian medicinal plant is traditionally used for rheumatism in the knee joint and pain in the muscles. AIM To investigate antinociceptive and antirheumatic activity of G. maderaspatana (L.) Poir. using experimental models. MATERIALS AND METHODS Antinociceptive activity of methanolic extract of G. maderaspatana (L.) Poir. ...

2012
Vanessa dos Santos Temponi Jucélia Barbosa da Silva Maria Silvana Alves Antônia Ribeiro José de Jesus Ribeiro Gomes de Pinho Célia Hitomi Yamamoto Miriam Aparecida Oliveira Pinto Glauciemar Del-Vechio-Vieira Orlando Vieira de Sousa

The ethanol extract from Vernonia polyanthes leaves (EEVP) was investigated for antinociceptive and anti-inflammatory effects at the doses (p.o.) of 100, 200 and 400 mg/kg in animal models. The extract reduced the number of abdominal contortions by 16.75% and 31.44% at a dose of 200 and 400 mg/kg, respectively. The results obtained showed that EEVP exerted a significant antinociceptive effect i...

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