نتایج جستجو برای: antiproliferative activity

تعداد نتایج: 1139196  

Journal: :Anais da Academia Brasileira de Ciencias 2010
Liana V Rossato Solange B Tedesco Haywood D Laughinghouse Júlia G Farias Fernando T Nicoloso

We evaluated the antiproliferative effect of infusions from Pluchea sagittalis using the Allium cepa test. Infusions in three concentrations (2.5, 5, and 25 g dm-3) of leaves cultivated in three environments (in vitro, acclimatized growth chamber, and field) were used. Six onion bulbs were used for each of the eight treatments, and the mitotic index was obtained from 6000 cells per treatment. I...

Journal: :Molecules 2013
Virginia Delgado Andrea Ibacache Verónica Arancibia Cristina Theoduloz Jaime A Valderrama

A variety of phenylaminoisoquinolinequinones were synthesized and tested for their antiproliferative activity against three human-tumor derived cancer cell lines. The new aminoquinones were prepared from 4-methoxycarbonyl-3-methylisoquinoline-5,8-quinone (1) via acid-induced amination and bromination reactions. Remarkable differences in antiproliferative activity were observed depending upon th...

Journal: :Acta poloniae pharmaceutica 2015
Andrzej Niewiadomy Alicja Skrzypek Joanna Matysiak Urszula Głaszcz Joanna Wietrzyk Elżbieta Krajewska-Kułak

A series of novel N,N-cyclic-2,4-dihydroxythiobenzamide derivatives is described. Test compounds were formed by the reaction of the commercially available reagents with sulfinylbis[(2,4-dihydroxyphenyl)methanethione] (STB). The chemical structures were confirmed by IR, 1H NMR, 13CNMR, EI-MS, and elemental analysis. For the estimation of potential activity in vitro, the MIC values against strain...

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