Tuberculosis is a great masquerader presenting in varied forms and in atypical locations. The myriad presentations of tuberculosis may complicate its diagnosis. We present two cases of acromioclavicular joint tuberculosis treated with a regimen of antitubercular drugs for 18 months leading to a complete resolution of symptoms.

Peripheral gangrene as a manifestation of tuberculosis is very uncommon. An 8 year old male child presented with non-healing ulcer over the sole of left foot, left inguinal tubercular lymphadenopathy with scrofloderma, tubercular pleural effusion and gangrene of the right fore foot. The child improved on antitubercular treatment.

Penile tuberculosis (TB) is an uncommon variety of genitourinary TB. It is either primary (via local spread) or secondary (spread of infection from other organs). We encountered a case of rapidly growing penile ulceration, resembling carcinoma. Biopsy revealed the classic picture of TB, which responded well to antitubercular treatment.

Tubercular esophagocutaneous fistula is a rare entity with only about five cases reported so far. To our best knowledge we herein report first case of tubercular esophagocutaneous fistula in neck of a child with a long tract which responded well to antitubercular treatment.

Primary tuberculosis of tonsils is rare. We reported a case of primary tonsillar tuberculosis in a 55-year-old female who presented with sore throat and enlargement of right tonsil. Histopathology revealed tuberculoisis. Complete resolution was found after antitubercular therapy. Tonsillar tuberculosis should be considered if patient is not responding to antibiotics.

A series of 2-amino-5-(4-(benzyloxy)benzyl)thiophene-3-carboxylic acid derivatives was designed and synthesized. The derivatives were evaluated for antitubercular activity against M. tuberculosis ATCC 27294 using the Microplate Alamar Blue Assay (MABA). Among them, compound 8b exhibited the most potent activity with MIC value of

Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.