Purpose: The aim of study was to determine the relation vitamin D receptor gene (VDR) polymorphisms TaqI (rs731236), ApaI (rs7975232), BsmI (rs1544410), FokI (rs10735810) with risk obesity, metabolic syndrome and hepatosteatosis in children.Materials methods: 130 obese healthy children age range between 10-16 years included this study. Anthropometric measurements, biochemical evaluations abdomi...

Thirty isolates of Listeria monocytogenes and 18 of L. innocua obtained from different short-ripened cheeses manufactured in Asturias (northern Spain), were compared with each other and with reference strains using serotype, phage type and pulsed-field restriction endonuclease digestion profiles analysis of the total DNA. Restriction enzymes ApaI and SmaI defined five clusters in L. monocytogen...

Annotation. Breast cancer is the most common diagnosed in women. In last 5 years, it has been 7.8 million women, and 2020, 685,000 deaths from breast were registered. The growing number of patients with this pathology cost therapy creates a need to study new methods diagnosis treatment. Therefore, detailed attention paid genetic risk factors for cancer, particular, VDR gene its polymorphisms Ap...

The vitamin D/Vitamin D receptor (VDR) axis is crucial for human health as it regulates the expression of genes involved in different functions, including calcium homeostasis, energy metabolism, cell growth and differentiation, immune responses. In particular, D/VDR complex both innate adaptive immunity. Autoimmune diseases are believed to arise from a genetic predisposition presence triggers s...