A sensitive and ultra-fast method utilizing the laser diode thermal desorption ion source using atmospheric pressure chemical ionization coupled to tandem mass spectrometry (LDTD-APCI-MS/MS) was developed for the quantitative analysis of BKM120, an investigational anticancer drug in human plasma. Samples originating from protein precipitation (PP) followed by salting-out assisted liquid-liquid ...

The lyophilized venom of the spider Paracoelotes birulai (Araneidae: Amaurobiidae) has been analyzed. A no. of acylpolyamines were found and sepd. By online coupled high-performance liq. chromatog. and atm.-pressure chem.-ionization mass spectrometry, the structures of the three most abundant compds. PB 490 (N-(16-guanidino-4-hydroxy-4,8,12-triazahexadecyl)-2-(4-hydroxyindol-3-yl)acetamide), PB...

Natural pavements are an important element of flights. Among other things, they allow the plane to be safely slowed down after it has exited runway. For this reason, load bearing capacity natural airfield and strength turf layer at a specified level required. Currently used testing methods, such as CBR (Californian Bearing Ratio) tests or probe test, separately do not give full image pavement t...

A set of titania–silica mixed oxide materials were prepared by a cosolvent-induced gelation method using ethanol and toluene as solvent cosolvent, respectively. These extensively characterized utilizing several characterization techniques assessed for phenol degradation under UV illumination. The follows first-order kinetics, fragmented products formed during the qualitatively identified high p...