The toxicity of endodontic materials is reviewed. The patient may be exposed by constituents leaching from the unset and set sealer and by accidental overfilling of the root canal. For most patients the exposure is believed to be below the threshold for a toxic effect. Most sealers exhibited a cytotoxic response, especially unset and the responses diminished with time after setting. Unset and n...

1 a z t g r b t w t t b e v p eriodontal accelerated osteogenic orthodontics PAOO) is a clinical procedure that combines selecive alveolar corticotomy, particulate bone grafting, nd the application of orthodontic forces. This proedure is theoretically based on the bone healing attern known as the regional acceleratory phenomnon (RAP). PAOO results in an increase in alveolar one width, shorter t...

introduction: objective: this study aimed to assess the possible variations in root canal anatomy and topography of the apices of first and second maxillary molars. materials and methods: a total of 67 first and second maxillary permanent molars were collected. access cavity was prepared and 2% methylene blue was injected. the teeth were demineralized by 5% nitric acid and cleared with methyl s...

Efficient wound healing is required to maintain the integrity of the intestinal epithelial barrier because of its constant exposure to a large variety of environmental stresses. This process implies a partial cell depolarization and the acquisition of a motile phenotype that involves rearrangements of the actin cytoskeleton. Here we address how polarized enterocytes harboring actin-rich apical ...

Endodontic treatment options for immature, nonvital teeth conventionally include surgical endodontics, apexification with calcium hydroxide, or single visit mineral trioxide aggregate plug. A new treatment option of revascularization has recently been introduced. It involves disinfecting the root canal system, providing a matrix of blood clot into which cells could grow, and sealing of the coro...

METHOD We report management of a failed revascularization/revitalization case, which could be due to inadequate removal of biofilm and bacteria in dentinal tubules. The use of an apical matrix barrier in form of a platelet-rich fibrin (PRF) membrane for stabilization of MTA in root end apexification procedure is described. The canal was cleansed of old MTA present in the cervical third using H ...

AIM To monitor and compare the outcome of periradicular surgery in teeth that had previously undergone surgical treatment versus teeth that were undergoing a surgical procedure for the first time. METHODOLOGY A total of 164 patients with 231 roots with previously unresolved periapical lesions were followed for up to 5 years following surgery. In all, 162 roots had received unsuccessful conven...

Several procedures have been recommended to induce the root end barrier formation in teeth with open apices. Conventional treatment for such cases will require many appointments with an average duration of 12.9 months. During this period, the root canal is susceptible to reinfection from around the provisional restoration, which may promote apical periodontitis and arrest of apical repair. Mine...