Carcinoid tumors are the most common neoplasm of the appendix. The clinical presentation of these lesions is often similar to that of acute appendicitis, or the tumors are asymptomatic. The carcinoids are commonly found incidentally during histopathological examination of the resected appendix following appendectomy or other abdominal procedures. Appendiceal carcinoids usually behave as benign ...

In the past decade, the clinical evaluation of patients with suspected appendicitis has dramatically improved in speed and accuracy due to the focused appendiceal CT developed at Massachusetts General Hospital. Clinical signs and laboratory tests are not sufficiently accurate to unequivocally diagnose or rule out appendicitis. Because of the seriousness of a perforated appendix, prior to the av...

BACKGROUND Due to concern that mucinous malignant or borderline ovarian neoplasms (MON) may represent metastatic deposits from appendiceal primaries, gynecologic oncologists routinely perform appendectomy in these cases. However, a multidisciplinary critique of this practice is lacking. METHODS The New England Case-Control study database was utilized to compare the effect of prior appendectom...

OBJECTIVE Mucinous cystadenocarcinoma of appendix is a rare entity. Differentiating mucinous cystadenocarcinoma from mucinous cystadenoma is very challenging and depends on establishing the presence of malignant cells in the appendix wall. The invasion may be very difficult to assess in some cases, especially in early stages of the disease, which could have devastating prognostic effects on pat...

Massive lower gastrointestinal bleed from an appendiceal stump is rare. Most often bleeding is in the peritoneal cavity or the retroperitoneum, rarely in the cecum. To our knowledge, massive bleeding from an appendiceal stump occurring 3 weeks after laparoscopic appendectomy and successfully treated endoscopically has not been reported previously. A 25-year-old man presented with the chief comp...

BACKGROUND There is little information available to inform choice of technique for appendiceal stump control in pediatric laparoscopic appendectomy (LA). We compared complications (stump leak, intra-abdominal abscess formation [IAA], surgical site infection [SSI]) in children undergoing LA for perforated (PA) and nonperforated appendicitis (NPA) by technique of appendiceal stump control. METH...

BACKGROUND The value of immunohistochemistry (IHC)-microarray analysis of pathological specimens in the management of patients is controversial, although preliminary data suggest potential benefit. We describe the characteristics of patients undergoing a commercially available IHC-microarray method in patients with peritoneal metastases (PM) and the feasibility of this technique in this populat...

Background: The role of appendicectomy in epithelial ovarian malignancy is debatable, and therefore to incorporate appendicectomy as a part of surgical staging especially in nonmucinous epithelial types of ovarian cancer is a real subject of controversy. The aim was to determine the incidence of appendiceal involvement in ovarian malignancy and the factors which increase the probability of invo...