Objective: The aim of this study was to evaluate the feasibility and safety of nonoperative treatment of acute nonperforated appendicitis with antibiotics in children. Methods: A pilot randomized controlled trial was performed comparing nonoperative treatment with antibiotics versus surgery for acute appendicitis in children. Patients with imaging-confirmed acute nonperforated appendicitis who ...

BACKGROUND The preoperative diagnosis of acute appendicitis is often inaccurate in pregnant women, and complicated appendicitis is associated with a high rate of fetal loss. The study objective was to evaluate rates of fetal loss and early delivery in pregnant patients undergoing appendectomy, using a large population-based database. STUDY DESIGN Using the California Inpatient File, we retros...

OBJECTIVE The aim of this study was to evaluate the feasibility and safety of nonoperative treatment of acute nonperforated appendicitis with antibiotics in children. METHODS A pilot randomized controlled trial was performed comparing nonoperative treatment with antibiotics versus surgery for acute appendicitis in children. Patients with imaging-confirmed acute nonperforated appendicitis who ...

Objective. To assess the predictive value of procalcitonin in detecting acute appendicitis (AP) in children, and to determine a cutoff value of procalcitonin which can safely include/exclude the diagnosis of acute appendicitis in children with acute abdominal pain. Methods. Prospective cohort study of children aged 5-17 years presenting to the emergency room with right lower quadrant (RLQ) tend...

Various limitations hinder the timely and accurate diagnosis of appendicitis in pediatric patients. The present study aims to investigate the potential of metabolomics and cytokine profiling for improving the diagnosis of pediatric appendicitis. Serum and plasma samples were collected from pediatric patients for metabolic and inflammatory mediator analyses respectively. Targeted metabolic profi...

PURPOSE To estimate the prevalence of acute appendicitis and the relationship between pregnancy and acute appendicitis among South Korean women in 2009. METHODS This was a cross-sectional study over 1 year period using a national registry data. We analyzed a national patient sample (n = 1,116,040) from a database complied by the South Korean National Health Insurance in 2009. RESULTS We ide...

BACKGROUND Abdominal ultrasonography (US) is the most commonly used diagnostic tool for diagnosing acute appendicitis, which is one of the most common causes of acute surgical abdomen. In this study, we examined the reliability of US for diagnosing acute appendicitis. METHODS In this prospective study, we performed abdominal US on 235 patients admitted to our surgical emergency department dur...

OBJECTIVE To suggest the use of the Pediatric appendicitis score (PAS) for diagnosing acute pediatric appendicitis in a community hospital. METHODS We retrospectively reviewed the data of 285 patients aged 3 to 17 years who underwent abdominal computed tomography (CT) for suspected acute appendicitis at a single community hospital. The PAS score was compared with the CT findings in the append...

Acute appendicitis is the most common cause of acute surgical abdomen during pregnancy. Our study was conducted to review our experience and diagnostic accuracy with MRI during pregnancy and clinical outcomes over a two year period. All pregnant women who underwent an MRI examination of the abdomen between January 2008 and January 2010 at Spectrum Health hospitals were included in the study. We...

To describe the epidemiology of appendicitis and appendectomy in the United States, the authors analyzed National Hospital Discharge Survey data for the years 1979-1984. Approximately 250,000 cases of appendicitis occurred annually in the United States during this period, accounting for an estimated 1 million hospital days per year. The highest incidence of primary positive appendectomy (append...