Abstract Background Chronic hepatitis C virus (HCV) infection represents a major health-related burden in Egypt. HCV is considered as cardiovascular risk factor. BNP (B-type natriuretic peptide) has been determined credible diagnostic and prognostic cardiac biomarker. We aimed to assess plasma HCV-positive Egyptian patients prior after eradication by direct-acting antiviral agents (DAAs) therap...

Background and Aim: Simple non-invasive tests for liver fibrosis like APRI, BARD, NFS, FIB-4 are easy to perform, cheap. Studies showed that fibroscan has good sensitivity in detecting NAFLD, but it is not available widely [1, 2]. There paucity of data about these noninvasive prediction Indian NAFLD patients. Aim this study compare various scores (APRI, FIB-4) with fibro-scan biopsy predict Met...

In this paper, the authors review the literature and share their experience of the principal biological markers of fibrosis for the evaluation of periportal fibrosis (PPF) caused by mansoni schistosomiasis. These biological markers are compared to diagnostic ultrasound (US) scans as means of grading PPF. We also review procollagen type I and III, collagen type IV, laminin, hyaluronic acid (HA),...

Results We assessed data from 64 patients (of which 27 were males 42%) with a median age of 54±14 (range: 23 to 64 years). The median fibrosis was 0.44±0.23 and the median necroinflammatory activity was 0.54±0.24. The median FIB-4 score was 1.89±3.23 at the second visit versus 1.26±2.07 at the third visit. The median APRI score was 1.18±1.67 at the second visit compared to 1.79 ±2.53 at the thi...

Abstract Background S100A14 is a novel significant individual from S100 proteins family. Its significance because of its part in tumorigenesis and metastasis process. Elevated level was associated with poor tumor differentiation. A relatively high dose capable to induce cell injuries. It discovered that seen at the extracellular medium. induces activation apoptotic mediators apoptosis. The aim ...

Methods Observational retrospective study. All HIV naive patients who started HAART from 1996 to 2006 were included. Concordance between FIB-4 and APRI scores was assessed using the weighted kappa coefficient. Rates of transition from lower classes to higher classes were estimated by Kaplan-Meier analysis. Cox regression models were applied to assess possible predictors both at baseline and dur...

BACKGROUND & AIMS There is a considerable burden of hepatitis C in Europe related to the lack of prompt diagnosis. We aimed to estimate the prevalence and related risk factors of HCV infections by the stages of liver fibrosis, using non-invasive methods, to understand testing needs in Poland. METHODS A cross-sectional study was conducted in 2012-2016 adopting a stratified random sampling of p...

Aim of the study Recently, novel serum markers modified by the body mass index z-score (BMI z-score) were proposed as a reliable noninvasive alternative for the detection of significant fibrosis and steatosis in children with chronic hepatitis C (CHC). The aim of this study was to evaluate the clinical usefulness of these biomarkers. Material and methods Thirty children aged 9.4 ± 3.7 years (...