BACKGROUND Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have been promising with regard to its revival in malaria therapy. The objective of this study was to assess the safety and efficacy of ...

In this article, we study the restriction of Zuckerman’s derived functor (g,K)-modules Aq(λ) to g′ for symmetric pairs of reductive Lie algebras (g, g′). When the restriction decomposes into irreducible (g′,K′)-modules, we give an upper bound for the branching law. In particular, we prove that each (g′,K′)-module occurring in the restriction is isomorphic to a submodule of Aq′ (λ ′) for a parab...

1.1. Fix a surjective morphism of fine monoids π : P → Q, and let j : AQ ↪→ AP be the corresponding closed immersion, where AP := Spec(k[P ]) and AQ := Spec(k[Q]). Assume further that the associated groups P gp and Q are torsion free, and that Q is sharp. Let TP (resp. TQ) denote the torus associated to the group P gp (resp. Q) so that TP acts on AP and TQ acts on AQ. The map π induces an inclu...

From extraction experiments and γ-activity measurements, the extraction constant corresponding to the equilibrium Na+(aq) + A-(aq) + 1(nb) left arrow over right arrow 1•Na+(nb) + A-(nb) taking place in the two-phase water-nitrobenzene system (A- = picrate, 1 = dibenzo-18-crown-6; aq = aqueous phase, nb = nitrobenzene phase) was evaluated as was log Kex (1•Na+, A-) = 1.7 ± 0.1. Further, the stab...

Knowledge extraction and acute forecasting are among the most challenging issues concerning the use of computational intelligence (CI) methods in real world applications. Both aspects are essential in cases where decision making is required, especially in domains directly related to the quality of life, like the quality of the atmospheric environment. In the present paper we emphasize on short ...

Objective: The beneficial effects of clove on toothache have been well documented. We have also previously shown the analgesic effects of clove essential oil. The present work was done to investigate the analgesic effects of the aqueous extract of clove using hot plate test. The possible role of opioid receptors in the analgesic effects of clove was also investigated using naloxone. Materials a...

Guidelines for Antimicrobial Stewardship Training and Practice Christine B Teng,1,5 MS(Clin Pharm), BCPS(AQ-ID), Winnie Lee,2 B.Pharm(Hon), BCPS(AQ-ID), Chay Leng Yeo,3 B.Pharm (Hon), BCPS, Siok Ying Lee,4 BSc(Pharmacy)(Hon), BCPS, Tat Ming Ng,5 BSc(Pharmacy)(Hon), Siang Fei Yeoh,3 MClinPharm, Wee Heng Lim,6 BSc(Pharmacy), Andrea L Kwa,2 PharmD, BCPS(AQ-ID), Koh Cheng Thoon,7 MBBS, MRCPCH, MMed...

Codes in finite projective spaces equipped with the subspace distance have been proposed for error control in random linear network coding. The resulting so-called Main Problem of Subspace Coding is to determine the maximum size Aq(v, d) of a code in PG(v−1,Fq) with minimum subspace distance d. Here we completely resolve this problem for d ≥ v − 1. For d = v − 2 we present some improved bounds ...

Presently, resin composites are indispensable for dental restorative treatment because of their favorable esthetic and mechanical properties. In particular, the adhesion of resin composites to dentin has been rapidly improved by progress resin adhesive systems. Of late, resin restorative procedures have been simplified with the development of adhesive systems with fewer processing steps. One of...